Adenosine is a nucleoside that impacts the cardiovascular system via the activation of its
membrane receptors, named A1R, A2AR, A2BR and A3R. Adenosine is released during …

Obstructive sleep apnea (OSA) is characterized by repeated episodes of intermittent hypoxia
(IH) and is recognized as an independent risk factor for vascular diseases that are mediated …

Abstract Currently available European Alpine Altitude Climate Treatment (AACT) programs
combine the physical characteristics of altitude with the avoidance of environmental triggers …

(1) Background: High-altitude hypoxia has been shown to affect the pharmacokinetic
properties of drugs. Although there is a high incidence of cardiovascular disease among …

Background Alterations in platelet function have been implicated in the pathophysiology of
COVID-19 since the beginning of the pandemic. While early reports linked hyperactivated …

Introduction Thrombosis stands as a significant contributor to both morbidity and mortality in
individuals afflicted with myeloproliferative neoplasms. This retrospective study investigated …

Objectives. Obstructive sleep apnoea (OSA) is associated with an increased risk of
cardiovascular disease, with alterations in coagulability suspected as the mediating factor …

Background Thromboelastogram (TEG) is an effective indicator that monitors the dynamic
changes of blood coagulation in real-time. It still remains controversial about the …

Platelet function testing is critical in the diagnosis of bleeding disorders and allows
monitoring of antiplatelet therapy. The gold standard assay, light transmission aggregometry …

Reduced oxygen tensions experienced at high altitudes are thought to predispose to
thrombosis, yet there are few studies linking hypoxia, platelet activation, and thrombosis …