The therapeutic limitations such as insufficient efficacy, drug resistance, metastasis, and
undesirable side effects are frequently caused by the long duration monotherapy based on …

Cancer is a devastating disease and is the second leading cause of death worldwide.
Surgery, chemotherapy (CT), and/or radiation therapy (RT) are the treatment of choice for …

Despite significant technological advancements in conventional therapies, cancer remains
one of the main causes of death worldwide. Although substantial progress has been made …

Multidrug resistance (MDR) promotes tumor recurrence and metastasis and heavily reduces
anticancer efficiency, which has become a primary reason for the failure of clinical …

Chemotherapy is one of the most commonly used clinical treatments among the currently
available cancer therapies. However, the phenomenon of Multidrug resistance (MDR) has …

Colorectal cancer (CRC) therapy is a big challenge, and seeking an effective and safe drug
is a pressing clinical need. Gambogic acid is a potent antineoplastic agent without the …

Previous research reported that the curcumin derivative (CU17) inhibited several cancer cell
growths in vitro. However, its anticancer potential against human lung cancer cells (A549 …

Cancer, with its diversity, heterogeneity, and complexity, is a significant contributor to global
morbidity, disability, and mortality, highlighting the necessity for transformative treatment …

Background Ferroptosis is a type of cell death caused by excessive iron-induced
peroxidation. It has been found to be involved in a variety of diseases, and natural products …

Breast cancer (BC) remains a significant health burden worldwide, necessitating the
development of innovative therapeutic strategies. The B-cell lymphoma 2 (Bcl-2) family …