Obesity as a disease

J Upadhyay, O Farr, N Perakakis, W Ghaly… - Medical …, 2018 - medical.theclinics.com
Obesity is a complex, chronic medical condition with a major negative impact on human
health. 1 Over the last 30 years, there has been an exponential growth in the prevalence of …

Body fat and risk of all-cause mortality: a systematic review and dose-response meta-analysis of prospective cohort studies

A Jayedi, TA Khan, D Aune, A Emadi… - International journal of …, 2022 - nature.com
Background/objectives We aimed to evaluate the relationships between body fat percentage
(BF%), fat mass (FM), fat mass index (FMI) and visceral (VAT) and subcutaneous adipose …

Prescription omega-3 fatty acids and their lipid effects: physiologic mechanisms of action and clinical implications

HE Bays, AP Tighe, R Sadovsky… - Expert review of …, 2008 - Taylor & Francis
Hypertriglyceridemia is a risk factor for atherosclerotic coronary heart disease. Very high
triglyceride (TG) levels (≥ 500 mg/dl [5.65 mmol/l]) increase the risk of pancreatitis. One …

Pathophysiology of dyslipidaemia in the metabolic syndrome

GD Kolovou, KK Anagnostopoulou… - Postgraduate medical …, 2005 - academic.oup.com
The insulin resistance/metabolic syndrome is characterised by the variable coexistence of
hyperinsulinaemia, obesity, dyslipidaemia, and hypertension. The pathogenesis of the …

Fetuin-A induces cytokine expression and suppresses adiponectin production

AM Hennige, H Staiger, C Wicke, F Machicao… - PloS one, 2008 - journals.plos.org
Background The secreted liver protein fetuin-A (AHSG) is up-regulated in hepatic steatosis
and the metabolic syndrome. These states are strongly associated with low-grade …

Shift work, and particularly permanent night shifts, promote dyslipidaemia: A systematic review and meta-analysis

F Dutheil, JS Baker, M Mermillod, M De Cesare, A Vidal… - Atherosclerosis, 2020 - Elsevier
Background and aims Shift work is common worldwide and linked to deleterious
cardiovascular effects that might be underlined by dyslipidemia. The aim of this systematic …

[HTML][HTML] Biological effects of bariatric surgery on obesity-related comorbidities

SF Noria, T Grantcharov - Canadian Journal of Surgery, 2013 - ncbi.nlm.nih.gov
The prevalence of obesity has increased so rapidly over the last few decades that it is now
considered a global epidemic. Obesity, defined as a body mass index (BMI) of 30 or more, is …

Surrogate markers of visceral adiposity in young adults: waist circumference and body mass index are more accurate than waist hip ratio, model of adipose distribution …

S Borruel, JF Moltó, M Alpanes, E Fernandez-Duran… - PloS one, 2014 - journals.plos.org
Surrogate indexes of visceral adiposity, a major risk factor for metabolic and cardiovascular
disorders, are routinely used in clinical practice because objective measurements of visceral …

Measurement and meaning of apolipoprotein AI and apolipoprotein B plasma levels

S Marcovina, CJ Packard - Journal of internal medicine, 2006 - Wiley Online Library
Apolipoproteins AI and B are structural components of lipoprotein particles, and also
determinants of the metabolic fate of the encapsulated lipid, cholesterol and triglyceride …

Inflammation and triglycerides partially mediate the effect of prepregnancy body mass index on the risk of preeclampsia

LM Bodnar, RB Ness, GF Harger… - American journal of …, 2005 - academic.oup.com
The objective of this study was to quantify the mediating role of inflammation and
triglycerides in the association between prepregnancy body mass index (weight (kg)/height …