[HTML][HTML] Mechanisms of SARS-CoV-2 entry into cells

CB Jackson, M Farzan, B Chen, H Choe - Nature reviews Molecular …, 2022 - nature.com
The unprecedented public health and economic impact of the COVID-19 pandemic caused
by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been …

Machinery, regulation and pathophysiological implications of autophagosome maturation

YG Zhao, P Codogno, H Zhang - Nature Reviews Molecular Cell …, 2021 - nature.com
Autophagy is a versatile degradation system for maintaining cellular homeostasis whereby
cytosolic materials are sequestered in a double-membrane autophagosome and …

The role of NSP6 in the biogenesis of the SARS-CoV-2 replication organelle

S Ricciardi, AM Guarino, L Giaquinto, EV Polishchuk… - Nature, 2022 - nature.com
Abstract SARS-CoV-2, like other coronaviruses, builds a membrane-bound replication
organelle to enable RNA replication. The SARS-CoV-2 replication organelle is composed of …

[HTML][HTML] Coronavirus biology and replication: implications for SARS-CoV-2

P V'kovski, A Kratzel, S Steiner, H Stalder… - Nature Reviews …, 2021 - nature.com
The SARS-CoV-2 pandemic and its unprecedented global societal and economic disruptive
impact has marked the third zoonotic introduction of a highly pathogenic coronavirus into the …

β-Coronaviruses use lysosomes for egress instead of the biosynthetic secretory pathway

S Ghosh, TA Dellibovi-Ragheb, A Kerviel, E Pak, Q Qiu… - Cell, 2020 - cell.com
Summary β-Coronaviruses are a family of positive-strand enveloped RNA viruses that
includes the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Much is …

COVID-19: Discovery, diagnostics and drug development

T Asselah, D Durantel, E Pasmant, G Lau… - Journal of …, 2021 - Elsevier
Summary Coronavirus disease 2019 (COVID-19) started as an epidemic in Wuhan in 2019,
and has since become a pandemic. Groups from China identified and sequenced the virus …

Structures and distributions of SARS-CoV-2 spike proteins on intact virions

Z Ke, J Oton, K Qu, M Cortese, V Zila, L McKeane… - Nature, 2020 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virions are surrounded by
a lipid bilayer from which spike (S) protein trimers protrude. Heavily glycosylated S trimers …

A highly photostable and bright green fluorescent protein

M Hirano, R Ando, S Shimozono, M Sugiyama… - Nature …, 2022 - nature.com
The low photostability of fluorescent proteins is a limiting factor in many applications of
fluorescence microscopy. Here we present StayGold, a green fluorescent protein (GFP) …

Cellular host factors for SARS-CoV-2 infection

J Baggen, E Vanstreels, S Jansen, D Daelemans - Nature Microbiology, 2021 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic has claimed millions of lives
and caused a global economic crisis. No effective antiviral drugs are currently available to …

SARS-CoV-2 structure and replication characterized by in situ cryo-electron tomography

S Klein, M Cortese, SL Winter… - Nature …, 2020 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the
COVID19 pandemic, is a highly pathogenic β-coronavirus. As other coronaviruses, SARS …