Gout is a common hyperuricaemic metabolic condition that leads to painful inflammatory
arthritis and a high comorbidity burden, especially cardiometabolic-renal (CMR) conditions …

Uric acid (UA) is the final product of purine metabolism in the human body, and impaired
purine metabolism can increase the uric acid in serum, finally resulting in hyperuricemia …

Gout and hyperuricemia are present in 25% and 60% of patients with chronic kidney
disease (CKD), respectively. Despite the common association, the role of uric acid in the …

Gout and chronic kidney disease (CKD) frequently coexist, but quality evidence to guide
gout management in people with CKD is lacking. Use of urate-lowering therapy (ULT) in the …

Xanthine oxidase inhibitors such as allopurinol and febuxostat have been the mainstay
urate-lowering therapy (ULT) for treating hyperuricaemia in patients with gout. However, not …

Gout and hyperuricaemia are two clinical situations associated with an elevated risk of
developing cardiovascular (heart failure, myocardial infarction, stroke) and metabolic and …

Abstract Purpose of Review In this review, we report on new findings regarding associations
of uric acid with kidney health. We discuss kidney stones, effects of uric acid in chronic …

The prevalence of patients with hyperuricemia or gout is increasing worldwide.
Hyperuricemia and gout are primarily attributed to genetic factors, along with lifestyle factors …

Gout is a common form of inflammatory arthritis where urate crystals deposit in joints and
surrounding tissues. With the high prevalence of gout, the standardized and effective …

Gout is characterized by monosodium urate (MSU) crystal deposits in and within joints.
These deposits result from persistent hyperuricaemia and most typically lead to recurrent …