Innate immune gene polymorphisms in tuberculosis
Tuberculosis (TB) is a leading cause worldwide of human mortality attributable to a single
infectious agent. Recent studies targeting candidate genes and “case-control” association …
infectious agent. Recent studies targeting candidate genes and “case-control” association …
Current findings, challenges and novel approaches in human genetic susceptibility to tuberculosis
The evidence for a human genetic component in susceptibility to tuberculosis (TB) is
incontrovertible. Quite apart from studies of rare disease events illustrating the importance of …
incontrovertible. Quite apart from studies of rare disease events illustrating the importance of …
Genome-wide analysis of the structure of the South African Coloured Population in the Western Cape
E De Wit, W Delport, CE Rugamika, A Meintjes… - Human genetics, 2010 - Springer
Admixed populations present unique opportunities to discover the genetic factors underlying
many multifactorial diseases. The geographical position and complex history of South Africa …
many multifactorial diseases. The geographical position and complex history of South Africa …
Genome-wide association study of ancestry-specific TB risk in the South African Coloured population
The worldwide burden of tuberculosis (TB) remains an enormous problem, and is
particularly severe in the admixed South African Coloured (SAC) population residing in the …
particularly severe in the admixed South African Coloured (SAC) population residing in the …
[HTML][HTML] Influence of genetic polymorphism towards pulmonary tuberculosis susceptibility
M Harishankar, P Selvaraj, R Bethunaickan - Frontiers in medicine, 2018 - frontiersin.org
Tuberculosis (TB) is still remains the major threat for human health worldwide. Several case-
control, candidate-gene, family studies and genome-wide association studies (GWAS) …
control, candidate-gene, family studies and genome-wide association studies (GWAS) …
Inflammation and tuberculosis: host‐directed therapies
A Zumla, M Rao, SK Parida… - Journal of Internal …, 2015 - Wiley Online Library
Tuberculosis (TB) is an airborne infectious disease that kills almost two million individuals
every year. Multidrug‐resistant (MDR) TB is caused by strains of Mycobacterium …
every year. Multidrug‐resistant (MDR) TB is caused by strains of Mycobacterium …
Genetic susceptibility in tuberculosis
JJ YIM, P Selvaraj - Respirology, 2010 - Wiley Online Library
The importance of host genetic factors in determining susceptibility to tuberculosis (TB) has
been studied extensively using various methods, such as case‐control, candidate gene and …
been studied extensively using various methods, such as case‐control, candidate gene and …
Past, present and future directions in human genetic susceptibility to tuberculosis
The historical impression that tuberculosis was an inherited disorder has come full circle and
substantial evidence now exists of the human genetic contribution to susceptibility to …
substantial evidence now exists of the human genetic contribution to susceptibility to …
[HTML][HTML] Interaction between host genes and Mycobacterium tuberculosis lineage can affect tuberculosis severity: Evidence for coevolution?
ML McHenry, J Bartlett, RP Igo Jr, EM Wampande… - PLoS …, 2020 - journals.plos.org
Genetic studies of both the human host and Mycobacterium tuberculosis (MTB) demonstrate
independent association with tuberculosis (TB) risk. However, neither explains a large …
independent association with tuberculosis (TB) risk. However, neither explains a large …
[HTML][HTML] Host genetics and tuberculosis: Theory of genetic polymorphism and tuberculosis
PP Aravindan - Lung India, 2019 - journals.lww.com
Materials and Methods: This is a special article compiled with reference to various case-
control studies, meta-analysis, and other research work on different genes and TB. The …
control studies, meta-analysis, and other research work on different genes and TB. The …