Cancer and degenerative diseases are major causes of morbidity and death, derived from
the permanent modification of key biopolymers such as DNA and regulatory proteins by …

Ethylene oxide (EtO), propylene oxide (PO) and epichlorohydrin (ECH) are important
industrial chemicals widely used as intermediates for various synthetic products. EtO and PO …

The Tenth Edition of Hunter's Diseases of Occupations has been fully revised and updated,
presenting all practitioners considering an occupational cause for a patient's condition with …

Objectives There are some common occupational agents and exposure circumstances for
which evidence of carcinogenicity is substantial but not yet conclusive for humans. Our …

Background: Exposure to chemicals that cause rodent mammary gland tumors is common,
but few studies have evaluated potential breast cancer risks of these chemicals in humans …

Background: The International Agency for Research on Cancer (IARC) Monographs
program assembles expert working groups who publish a critical review and evaluation of …

Objective This systematic review aims to synthesize current knowledge on Propylene Oxide
(PO) in human exhaled breath, examining its presence across various biological matrices …

Haemoglobin adducts are highly valuable biomarkers of cumulative exposure to
carcinogenic substances. We have developed and applied an analytical method for the …

We evaluated our data on the occupational exposure to styrene in lamination workers. The
battery of parameters included markers of external and internal exposure and biomarkers of …

Volatile organic compounds (VOCs) exert their carcinogenic activity through the production
of epoxide metabolites. Because of their high reactivity some epoxides are also produced in …