Dementia with Lewy bodies and Parkinson's disease-dementia: current concepts and controversies

KA Jellinger - Journal of neural transmission, 2018 - Springer
Dementia with Lewy bodies (DLB) and Parkinson's disease-dementia (PDD), although
sharing many clinical, neurochemical and morphological features, according to DSM-5, are …

From menopause to neurodegeneration—molecular basis and potential therapy

YJ Cheng, CH Lin, HY Lane - International journal of molecular sciences, 2021 - mdpi.com
The impacts of menopause on neurodegenerative diseases, especially the changes in
steroid hormones, have been well described in cell models, animal models, and humans …

Cognitive fluctuations in Lewy body dementia: towards a pathophysiological framework

E Matar, JM Shine, GM Halliday, SJG Lewis - Brain, 2020 - academic.oup.com
Fluctuating cognition is a complex and disabling symptom that is seen most frequently in the
context of Lewy body dementias encompassing dementia with Lewy bodies and Parkinson's …

Hallucinations, somatic‐functional disorders of PD‐DLB as expressions of thalamic dysfunction

M Onofrj, AJ Espay, L Bonanni, S Delli Pizzi… - Movement …, 2019 - Wiley Online Library
Hallucinations, delusions, and functional neurological manifestations (conversion and
somatic symptom disorders) of Parkinson's disease (PD) and dementia with Lewy bodies …

The central role of the Thalamus in psychosis, lessons from neurodegenerative diseases and psychedelics

M Onofrj, M Russo, S Delli Pizzi, D De Gregorio… - Translational …, 2023 - nature.com
The PD-DLB psychosis complex found in Parkinson's disease (PD) and Dementia with Lewy
Bodies (DLB) includes hallucinations, Somatic Symptom/Functional Disorders, and …

Endocannabinoid modulation in neurodegenerative diseases: In pursuit of certainty

A Vasincu, RN Rusu, DC Ababei, M Larion, W Bild… - Biology, 2022 - mdpi.com
Simple Summary Neurodegenerative diseases represent an important cause of morbidity
and mortality worldwide. Existing therapeutic options are limited and focus mostly on …

Clinical, neuropathological and genetic features of Lewy body dementias

D Hansen, H Ling, T Lashley, JL Holton… - Neuropathology and …, 2019 - Wiley Online Library
Lewy body dementias are the second most common neurodegenerative dementias after
Alzheimer's disease and include dementia with Lewy bodies and Parkinson's disease …

When the central integrator disintegrates: A review of the role of the thalamus in cognition and dementia

JM Biesbroek, MG Verhagen… - Alzheimer's & …, 2024 - Wiley Online Library
The thalamus is a complex neural structure with numerous anatomical subdivisions and
intricate connectivity patterns. In recent decades, the traditional view of the thalamus as a …

The evolution-driven signature of Parkinson's disease

NJ Diederich, T Uchihara, S Grillner, CG Goetz - Trends in Neurosciences, 2020 - cell.com
In this review, we approach Parkinson's disease (PD) in the context of an evolutionary
mismatch of central nervous system functions. The neurons at risk have hyperbranched …

Clinical and diagnostic implications of Alzheimer's disease copathology in Lewy body disease

L Barba, S Abu-Rumeileh, H Barthel, F Massa… - Brain, 2024 - academic.oup.com
Concomitant Alzheimer's disease (AD) pathology is a frequent event in the context of Lewy
body disease (LBD), occurring in approximately half of all cases. Evidence shows that LBD …