Mechanisms, consequences, and prevention of coronary graft failure

M Gaudino, C Antoniades, U Benedetto, S Deb… - Circulation, 2017 - Am Heart Assoc
Graft failure occurs in a sizeable proportion of coronary artery bypass conduits. We herein
review relevant current evidence to give an overview of the incidence, pathophysiology, and …

Preventing treatment failures in coronary artery disease: what can we learn from the biology of in-stent restenosis, vein graft failure, and internal thoracic arteries?

C Spadaccio, C Antoniades, A Nenna… - Cardiovascular …, 2020 - academic.oup.com
Coronary artery disease (CAD) remains one of the most important causes of morbidity and
mortality worldwide, and the availability of percutaneous or surgical revascularization …

Identification of inflammatory mediators and their modulation by strategies for the management of the systemic inflammatory response during cardiac surgery

R Hall - Journal of Cardiothoracic and Vascular Anesthesia, 2013 - jcvaonline.com
THE SYSTEMIC INFLAMMATORY RESPONSE (man-ifested by pyrexia, leukocytosis,
tachycardia, hypotension, tissue fluid accumulation, and organ failure) is generated during …

Cardiovascular tissue engineering: state of the art

DS Vara, HJ Salacinski, RY Kannan, L Bordenave… - Pathologie …, 2005 - Elsevier
In patients requiring coronary or peripheral vascular bypass procedures, autogenous arterial
or vein grafts remain as the conduit of choice even in the case of redo patients. It is in this …

High-pressure distention of the saphenous vein during preparation results in increased markers of inflammation: a potential mechanism for graft failure

MS Khaleel, TA Dorheim, MJ Duryee… - The Annals of thoracic …, 2012 - Elsevier
BACKGROUND: Coronary artery disease is the single leading cause of death in the United
States. Commonly it is treated with coronary bypass grafting using the saphenous vein (SV) …

Histopathological changes and expression of adhesion molecules and laminin in varicose veins

Aunapuu, Arend - Vasa, 2005 - econtent.hogrefe.com
Background: Although varicose disease is a common pathology, etiologic factors
predisposing to dilatation, elongation and tortuosity of the saphenous vein are not yet well …

Consensus statement—graft treatment in cardiovascular bypass graft surgery

MY Emmert, J Bonatti, E Caliskan… - Frontiers in …, 2024 - frontiersin.org
Coronary artery bypass grafting (CABG) is and continues to be the preferred
revascularization strategy in patients with multivessel disease. Graft selection has been …

Oral intake of hydrogen-rich water inhibits intimal hyperplasia in arterialized vein grafts in rats

Q Sun, T Kawamura, K Masutani, X Peng… - Cardiovascular …, 2012 - academic.oup.com
Aims Arterialized vein grafts often fail due to intimal hyperplasia. Hydrogen potently protects
organs and cells from many insults via its anti-inflammatory and antioxidant properties. We …

Pressure control during preparation of saphenous veins

FD Li, S Eagle, C Brophy, KM Hocking, M Osgood… - JAMA …, 2014 - jamanetwork.com
Importance Long-term patency of human saphenous veins (HSVs) used as autologous
conduits for coronary artery bypass grafting (CABG) procedures remains limited because of …

Biomechanics and mechanobiology of saphenous vein grafts

KJ Gooch, MS Firstenberg… - Journal of …, 2018 - asmedigitalcollection.asme.org
Within several weeks of use as coronary artery bypass grafts (CABG), saphenous veins (SV)
exhibit significant intimal hyperplasia (IH). IH predisposes vessels to thrombosis and …