Phosphoglycerate kinase: structural aspects and functions, with special emphasis on the enzyme from Kinetoplastea
M Rojas-Pirela, D Andrade-Alviárez… - Open …, 2020 - royalsocietypublishing.org
Phosphoglycerate kinase (PGK) is a glycolytic enzyme that is well conserved among the
three domains of life. PGK is usually a monomeric enzyme of about 45 kDa that catalyses …
three domains of life. PGK is usually a monomeric enzyme of about 45 kDa that catalyses …
Domestic animal proteomics in the 21st century: A global retrospective and viewpoint analysis
Animal production and health are of significant economic importance, particularly regarding
the world food supply. Animal and veterinary sciences have evolved immensely in the past …
the world food supply. Animal and veterinary sciences have evolved immensely in the past …
Heat shock protein 90 as a drug target against protozoan infections: biochemical characterization of HSP90 from Plasmodium falciparum and Trypanosoma evansi …
Using a pharmacological inhibitor of Hsp90 in cultured malarial parasite, we have previously
implicated Plasmodium falciparum Hsp90 (PfHsp90) as a drug target against malaria. In this …
implicated Plasmodium falciparum Hsp90 (PfHsp90) as a drug target against malaria. In this …
[HTML][HTML] Landscapes of protein posttranslational modifications of African Trypanosoma parasites
N Zhang, N Jiang, K Zhang, L Zheng, D Zhang, X Sang… - Iscience, 2020 - cell.com
Proteins of all living cells undergo a myriad of post-translational modifications (PTMs) that
are critical to multifarious life processes. In this study, we describe the first comprehensive …
are critical to multifarious life processes. In this study, we describe the first comprehensive …
Quinapyramine sulfate-loaded sodium alginate nanoparticles show enhanced trypanocidal activity
Aim: To reduce the dose, toxic effects and to ensure sustained release of quinapyramine
sulfate (QS), a highly effective drug against Trypanosoma evansi. Materials & methods: QS …
sulfate (QS), a highly effective drug against Trypanosoma evansi. Materials & methods: QS …
Nanotechnology enabled the enhancement of antitrypanosomal activity of piperine against Trypanosoma evansi
Nanoencapsulation is the promising approach to enhance the therapeutic potential of a
drug. In the present investigation, piperine-loaded nanocapsules (NCs) was prepared and …
drug. In the present investigation, piperine-loaded nanocapsules (NCs) was prepared and …
Infection of the brown alga Ectocarpus siliculosus by the oomycete Eurychasma dicksonii induces oxidative stress and halogen metabolism
M Strittmatter, LJ Grenville‐Briggs… - Plant, cell & …, 2016 - Wiley Online Library
Pathogens are increasingly being recognized as key evolutionary and ecological drivers in
marine ecosystems. Defence mechanisms of seaweeds, however, have mostly been …
marine ecosystems. Defence mechanisms of seaweeds, however, have mostly been …
Molecular tools-advances, opportunities and prospects for the control of parasites of veterinary importance
The recent advancement in genome sequencing facilities, proteomics, transcriptomics, and
metabolomics of eukaryotes have opened door for employment of molecular diagnostic …
metabolomics of eukaryotes have opened door for employment of molecular diagnostic …
Identification of proteins responding to pathogen-infection in the red alga Pyropia yezoensis using iTRAQ quantitative proteomics
Background Pyropia yezoensis is an important marine crop which, due to its high protein
content, is widely used as a seafood in China. Unfortunately, red rot disease, caused by …
content, is widely used as a seafood in China. Unfortunately, red rot disease, caused by …
Naphthoquinone derivatives exhibit apoptosis-like effect and anti-trypanosomal activity against Trypanosoma evansi
Trypanosoma evansi is an extracellular flagellate blood protozoan parasite and an
etiological agent of animal trypanosomosis. Presently, only a few drugs are registered and …
etiological agent of animal trypanosomosis. Presently, only a few drugs are registered and …