Possibility of magnesium supplementation for supportive treatment in patients with COVID-19
CF Tang, H Ding, RQ Jiao, XX Wu, LD Kong - European journal of …, 2020 - Elsevier
Magnesium as an enzymatic activator is essential for various physiological functions such as
cell cycle, metabolic regulation, muscle contraction, and vasomotor tone. A growing body of …
cell cycle, metabolic regulation, muscle contraction, and vasomotor tone. A growing body of …
DNA topoisomerases: Advances in understanding of cellular roles and multi‐protein complexes via structure‐function analysis
DNA topoisomerases, capable of manipulating DNA topology, are ubiquitous and
indispensable for cellular survival due to the numerous roles they play during DNA …
indispensable for cellular survival due to the numerous roles they play during DNA …
Conductive Two-Dimensional Magnesium Metal–Organic Frameworks for High-Efficiency O2 Electroreduction to H2O2
Direct electrosynthesis of H2O2 via a two-electron oxygen reduction reaction (2e–ORR)
under ambient conditions is emerging as a promising solution toward on-site applications for …
under ambient conditions is emerging as a promising solution toward on-site applications for …
Catalytic active centers beyond transition metals: Atomically dispersed alkaline-earth metals for the electroreduction of nitrate to ammonia
Alkaline-earth (AE) metals have rarely been reported to be the active centers in
heterogeneous catalysis. However, in nature, Mg cofactors in enzymes exhibit super activity …
heterogeneous catalysis. However, in nature, Mg cofactors in enzymes exhibit super activity …
[HTML][HTML] Turning main-group element magnesium into a highly active electrocatalyst for oxygen reduction reaction
It is known that the main-group metals and their related materials show poor catalytic activity
due to a broadened single resonance derived from the interaction of valence orbitals of …
due to a broadened single resonance derived from the interaction of valence orbitals of …
[HTML][HTML] Recent developments in topoisomerase-targeted cancer chemotherapy
KE Hevener, TA Verstak, KE Lutat, DL Riggsbee… - … pharmaceutica sinica B, 2018 - Elsevier
The DNA topoisomerase enzymes are essential to cell function and are found ubiquitously
in all domains of life. The various topoisomerase enzymes perform a wide range of functions …
in all domains of life. The various topoisomerase enzymes perform a wide range of functions …
[HTML][HTML] Exploiting bacterial DNA gyrase as a drug target: current state and perspectives
F Collin, S Karkare, A Maxwell - Applied microbiology and biotechnology, 2011 - Springer
DNA gyrase is a type II topoisomerase that can introduce negative supercoils into DNA at
the expense of ATP hydrolysis. It is essential in all bacteria but absent from higher …
the expense of ATP hydrolysis. It is essential in all bacteria but absent from higher …
Type IIA topoisomerase inhibition by a new class of antibacterial agents
Despite the success of genomics in identifying new essential bacterial genes, there is a lack
of sustainable leads in antibacterial drug discovery to address increasing multidrug …
of sustainable leads in antibacterial drug discovery to address increasing multidrug …
[HTML][HTML] Metal complexes of quinolone antibiotics and their applications: an update
V Uivarosi - Molecules, 2013 - mdpi.com
Quinolones are synthetic broad-spectrum antibiotics with good oral absorption and excellent
bioavailability. Due to the chemical functions found on their nucleus (a carboxylic acid …
bioavailability. Due to the chemical functions found on their nucleus (a carboxylic acid …
[HTML][HTML] The current case of quinolones: synthetic approaches and antibacterial activity
Quinolones are broad-spectrum synthetic antibacterial drugs first obtained during the
synthesis of chloroquine. Nalidixic acid, the prototype of quinolones, first became available …
synthesis of chloroquine. Nalidixic acid, the prototype of quinolones, first became available …