Laser ablation–inductively coupled plasma–mass spectrometry imaging in biology
Elemental imaging gives insight into the fundamental chemical makeup of living organisms.
Every cell on Earth is comprised of a complex and dynamic mixture of the chemical elements …
Every cell on Earth is comprised of a complex and dynamic mixture of the chemical elements …
Emerging computational methods in mass spectrometry imaging
Mass spectrometry imaging (MSI) is a powerful analytical technique that generates maps of
hundreds of molecules in biological samples with high sensitivity and molecular specificity …
hundreds of molecules in biological samples with high sensitivity and molecular specificity …
[HTML][HTML] Correlated multimodal imaging in life sciences: expanding the biomedical horizon
The frontiers of bioimaging are currently being pushed toward the integration and correlation
of several modalities to tackle biomedical research questions holistically and across multiple …
of several modalities to tackle biomedical research questions holistically and across multiple …
Multimodal imaging based on vibrational spectroscopies and mass spectrometry imaging applied to biological tissue: a multiscale and multiomics review
Molecular imaging has the potential to unearth important spatial and temporal relationships
in biological systems, including intercellular signaling as well as environmentally-cued …
in biological systems, including intercellular signaling as well as environmentally-cued …
[HTML][HTML] Epilipidomics of senescent dermal fibroblasts identify lysophosphatidylcholines as pleiotropic senescence-associated secretory phenotype (SASP) factors
MS Narzt, V Pils, C Kremslehner, IM Nagelreiter… - Journal of investigative …, 2021 - Elsevier
During aging, skin accumulates senescent cells. The transient presence of senescent cells,
followed by their clearance by the immune system, is important in tissue repair and …
followed by their clearance by the immune system, is important in tissue repair and …
[HTML][HTML] Artificial intelligence to decode cancer mechanism: beyond patient stratification for precision oncology
The multitude of multi-omics data generated cost-effectively using advanced high-
throughput technologies has imposed challenging domain for research in Artificial …
throughput technologies has imposed challenging domain for research in Artificial …
Mass spectrometry imaging to detect lipid biomarkers and disease signatures in cancer
M Holzlechner, E Eugenin, B Prideaux - Cancer reports, 2019 - Wiley Online Library
Background Current methods to identify, classify, and predict tumor behavior mostly rely on
histology, immunohistochemistry, and molecular determinants. However, better predictive …
histology, immunohistochemistry, and molecular determinants. However, better predictive …
High-resolution imaging and single-cell analysis via laser ablation-inductively coupled plasma-mass spectrometry for the determination of membranous receptor …
T Van Acker, T Buckle, SJM Van Malderen… - Analytica chimica …, 2019 - Elsevier
This work evaluates the possibility of placement of high-resolution imaging and single-cell
analysis via laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS) …
analysis via laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS) …
[HTML][HTML] Mass spectrometry techniques for imaging and detection of metallodrugs
S Theiner, A Schoeberl, A Schweikert… - Current Opinion in …, 2021 - Elsevier
Undoubtedly, metallomic approaches based on mass spectrometry have evolved into
essential tools supporting the drug development of novel metal-based anticancer drugs …
essential tools supporting the drug development of novel metal-based anticancer drugs …
Mass spectrometry imaging of metals in tissues and cells: Methods and biological applications
BL Gorman, SV Torti, FM Torti, CR Anderton - Biochimica et Biophysica …, 2024 - Elsevier
Background Metals are pervasive throughout biological processes, where they play
essential structural and catalytic roles. Metals can also exhibit deleterious effects on human …
essential structural and catalytic roles. Metals can also exhibit deleterious effects on human …