Insights into the chemistry and therapeutic potential of furanones: A versatile pharmacophore

A Husain, SA Khan, F Iram, MA Iqbal, M Asif - European Journal of …, 2019 - Elsevier
Furanone, a five-membered heteroaromatic ring containing oxygen atom, is of immense
pharmaceutical importance. Presence of this nucleus in biologically active compounds of …

[HTML][HTML] Quinoline based furanones and their nitrogen analogues: Docking, synthesis and biological evaluation

SL Khokra, P Kaushik, MM Alam, MS Zaman… - Saudi Pharmaceutical …, 2016 - Elsevier
A small library of twenty-four quinoline based butenolides also known as furanones and
their nitrogen analogues was prepared by using two different aroylpropionic acids, viz. 3-(2 …

Synthesis, reactions and biological activity of 3-arylidene-5-(4-methylphenyl)-2 (3H)-furanones?

A Husain, MM Alam, N Siddiqui - Journal of the Serbian Chemical …, 2009 - doiserbia.nb.rs
3-Arylidene-5-(4-methylphenyl)-2 (3H)-furanones 2a-m were prepared from 3-(4-methyl-
benzoyl) propanoic acid 1 and several aromatic aldehydes. Some of the selected furanones …

Green Synthesis of 3‐Alkylidenefuran‐2‐ones by Palladium‐Catalyzed Cyclocarbonylation of Aryl Iodides with Benzyl Acetylenes in 2‐MeTHF

J Zhan, J Chen, L Wei, M Cai - European Journal of Organic …, 2024 - Wiley Online Library
A novel, highly efficient heterogeneous palladium‐catalyzed carbonylative cyclization of aryl
iodides and benzyl acetylenes has been developed under an atmospheric pressure of CO …

3-arylidene-5-(4-isobutylphenyl)-2 (3H)-furanones: a new series of anti-inflammatory and analgesic compounds having antimicrobial activity

MM Alam, A Husain, SM Hasan, S Khanna… - Journal of Enzyme …, 2010 - Taylor & Francis
An ideal anti-inflammatory drug should have the desired effect in minimum dose with
minimum side effects. Antimicrobial actions associated with such agents will be an added …

Lactate dehydrogenase inhibitor and antiepileptic drug containing the same

T Inoue, N Sada - US Patent 10,350,192, 2019 - Google Patents
The invention provides a lactate dehydrogenase inhibitor that makes it possible to suppress
refractory epilepsy in which conventional antiepileptic drugs are ineffective, and an …

[PDF][PDF] Biological evaluation of 2-arylidene-4-(4-methoxy/phenoxy-phenyl) but-3-en-4-olides

A Husain - scholar.archive.org
A series of nine 2-arylidene-4-(4-methoxy/phenoxy-phenyl) but-3-en-4-olides (I-IX) were
screened against Pheretima posthuma earthworm species to assess the anthelmintic activity …

[引用][C] SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL INVESTIGATIONS ON METAL COMPLEXES OF 2-[5-ACETYL-2, 4-DIHYDROXYBENZYL]-1H …

MR SOLANKI, GD ACHARYA, MV HATHI

[引用][C] SYNTHESIS OF 2-ARYLIDENE-4-(SUBSTITUTED ARYL) BUT-3-EN-4-OLIDES AND EVALUATION OF THEIR ANTIBACTERIAL AND ANTI-INFLAMMATORY

A HUSAIN, MM ALAM, MS ZAMAN, MV ISMAIL

[引用][C] COX-2 inhibitory and GABAergic activity of newly synthesized 2 (3H)-furanone

UP Muzaffarnagar