Restless legs syndrome (RLS) is characterized by an uncomfortable urge to move the legs
while at rest, relief upon movement or getting up to walk, and worsened symptom severity at …

Restless legs syndrome (RLS) has gained considerable attention in the recent years: nearly
50 community-based studies have been published in the last decade around the world. The …

Background In 2003, following a workshop at the National Institutes of Health, the
International Restless Legs Syndrome Study Group (IRLSSG) developed updated …

Although commonly observed in clinical practice, the heterogeneity of obstructive sleep
apnoea (OSA) clinical presentation has not been formally characterised. This study was the …

The aim was to assess the prevalence of obstructive sleep apnoea (OSA) as defined by an
apnoea–hypopnea index (AHI)≥ 15 in the middle-aged general population, and the …

Restless legs syndrome (RLS), also known as Willis–Ekbom Disease (WED), is a
sensorimotor disorder for which the exact pathophysiology remains unclear. Brain iron …

This systematic review, meta‐analysis and meta‐regression assessed the prevalence of
restless legs syndrome (RLS) in the general adult population. Studies identified in Scopus …

There are several hundred of epidemiological studies assessing different sleep complaints
and disorders in the general population. This article summarizes the main findings of these …

Three major clinical features of restless leg syndrome/Willis-Ekbom disease (RLS/WED)
unique for common neurologic disorders enabled somewhat surprising pathophysiologic …

The aim of this overview was to outline the pathophysiology, common comorbidities and
current therapeutic modalities in the treatment/management of restless legs syndrome (RLS) …