Immunotherapy, represented by immune checkpoint inhibitors (ICIs), has greatly improved
the clinical efficacy of malignant tumor therapy. ICI-mediated antitumor responses depend …

Cancer immunotherapy (CIT) has gained increasing attention and made promising progress
in recent years, especially immune checkpoint inhibitors such as antibodies blocking …

The cytosolic innate immune sensor cyclic GMP-AMP synthase-stimulator of interferon
genes (cGAS-STING) pathway is crucial for priming adaptive antitumour immunity through …

Despite the challenges in treating glioblastomas (GBMs) with immune adjuvants, increasing
evidence suggests that targeting the immune cells within the tumor microenvironment (TME) …

The therapeutic effect of cancer immunotherapy is restrained by limited patient response
rate caused by 'cold'tumors with an intrinsically immunosuppressive tumor …

Neurological diseases are a major global health challenge, affecting hundreds of millions of
people worldwide. Ultrasound therapy plays an irreplaceable role in the treatment of …

A surge of research in intracellular delivery technologies is underway with the increased
innovations in cell‐based therapies and cell reprogramming. Particularly, physical cell …

Scaling down the size of microbubble contrast agents to the nanometer level holds the
promise for noninvasive cancer therapy. However, the small size of nanobubbles limits the …

Recently, emerging evidence has demonstrated that cavitation actually creates important
bidirectional channels on biological barriers for both intratumoral drug delivery and …

Noninvasive ultrasound surgery can be achieved using focused ultrasound to locally affect
the targeted site without damaging intervening tissues. Mechanical ablation and histotripsy …