Defining dry eye from a clinical perspective

K Tsubota, SC Pflugfelder, Z Liu, C Baudouin… - International journal of …, 2020 - mdpi.com
Over the past decades, the number of patients with dry eye disease (DED) has increased
dramatically. The incidence of DED is higher in Asia than in Europe and North America …

TFOS DEWS II definition and classification report

JP Craig, KK Nichols, EK Akpek, B Caffery, HS Dua… - The ocular …, 2017 - Elsevier
The goals of the TFOS DEWS II Definition and Classification Subcommittee were to create
an evidence-based definition and a contemporary classification system for dry eye disease …

Tfos dews ii epidemiology report

F Stapleton, M Alves, VY Bunya, I Jalbert, K Lekhanont… - The ocular …, 2017 - Elsevier
The subcommittee reviewed the prevalence, incidence, risk factors, natural history, morbidity
and questionnaires reported in epidemiological studies of dry eye disease (DED). A meta …

[HTML][HTML] NOV03 for dry eye disease associated with meibomian gland dysfunction: results of the randomized phase 3 GOBI study

J Tauber, GJ Berdy, DL Wirta, S Krösser, JL Vittitow… - Ophthalmology, 2023 - Elsevier
Objective To evaluate the efficacy and safety of NOV03 (perfluorohexyloctane) ophthalmic
drop in patients with dry eye disease (DED) associated with meibomian gland dysfunction …

[HTML][HTML] New perspectives on dry eye definition and diagnosis: a consensus report by the Asia Dry Eye Society

K Tsubota, N Yokoi, J Shimazaki, H Watanabe… - The ocular …, 2017 - Elsevier
For the last 20 years, a great amount of evidence has accumulated through epidemiological
studies that most of the dry eye disease encountered in daily life, especially in video display …

[HTML][HTML] The pathophysiology, diagnosis, and treatment of dry eye disease

EM Messmer - Deutsches Ärzteblatt International, 2015 - ncbi.nlm.nih.gov
Background Dry eye disease (DED) is common; its prevalence around the world varies from
5% to 34%. Its putative pathogenetic mechanisms include hyperosmolarity of the tear film …

Revisiting the vicious circle of dry eye disease: a focus on the pathophysiology of meibomian gland dysfunction

C Baudouin, EM Messmer, P Aragona… - British Journal of …, 2016 - bjo.bmj.com
Meibomian gland dysfunction (MGD) is the most frequent cause of dry eye disease (DED).
Eyelid inflammation, microbial growth, associated skin disorders as well as potentially …

Dry eye disease associated with meibomian gland dysfunction: focus on tear film characteristics and the therapeutic landscape

JD Sheppard, KK Nichols - Ophthalmology and Therapy, 2023 - Springer
Meibomian gland dysfunction (MGD) is highly prevalent and is the leading cause of
evaporative dry eye disease (DED). MGD is characterized by a reduction in meibum …

Distribution of aqueous-deficient and evaporative dry eye in a clinic-based patient cohort: a retrospective study

MA Lemp, LA Crews, AJ Bron, GN Foulks, BD Sullivan - Cornea, 2012 - journals.lww.com
Purpose: To evaluate in a general clinic-based cohort of patients with dry eye disease (DED)
the distribution of patients with aqueous-deficient or evaporative subtype of DED. Methods …

[HTML][HTML] NOV03 for signs and symptoms of dry eye disease associated with meibomian gland dysfunction: the randomized phase 3 MOJAVE study

JD Sheppard, F Kurata, AT Epitropoulos… - American Journal of …, 2023 - Elsevier
Purpose To evaluate the efficacy and safety of NOV03 (perfluorohexyloctane) ophthalmic
drop for the treatment of signs and symptoms of dry eye disease (DED) associated with …