Stochastic mechano-chemical kinetics of molecular motors: a multidisciplinary enterprise from a physicist's perspective

D Chowdhury - Physics Reports, 2013 - Elsevier
A molecular motor is made of either a single macromolecule or a macromolecular complex.
Just like their macroscopic counterparts, molecular motors “transduce” input energy into …

Intracellular transport driven by cytoskeletal motors: General mechanisms and defects

C Appert-Rolland, M Ebbinghaus, L Santen - Physics Reports, 2015 - Elsevier
Cells are the elementary units of living organisms, which are able to carry out many vital
functions. These functions rely on active processes on a microscopic scale. Therefore, they …

Kinesin 1 drives autolysosome tubulation

W Du, QP Su, Y Chen, Y Zhu, D Jiang, Y Rong… - Developmental cell, 2016 - cell.com
Autophagic lysosome reformation (ALR) plays an important role in maintaining lysosome
homeostasis. During ALR, lysosomes are reformed by recycling lysosomal components from …

Calibration of optical tweezers for in vivo force measurements: how do different approaches compare?

Y Jun, SK Tripathy, BRJ Narayanareddy… - Biophysical journal, 2014 - cell.com
There is significant interest in quantifying force production inside cells, but since conditions
in vivo are less well controlled than those in vitro, in vivo measurements are challenging. In …

Emergent spatiotemporal organization in stochastic intracellular transport dynamics

K Joshi, HM York, CS Wright, RR Biswas… - Annual Review of …, 2024 - annualreviews.org
The interior of a living cell is an active, fluctuating, and crowded environment, yet it maintains
a high level of coherent organization. This dichotomy is readily apparent in the intracellular …

Pattern formation and polarity sorting of driven actin filaments on lipid membranes

A Sciortino, AR Bausch - Proceedings of the National …, 2021 - National Acad Sciences
Collective motion of active matter is ubiquitously observed, ranging from propelled colloids
to flocks of bird, and often features the formation of complex structures composed of agents …

Coordination and collective properties of molecular motors: theory

T Guérin, J Prost, P Martin, JF Joanny - Current opinion in cell biology, 2010 - Elsevier
Many cellular processes require molecular motors to produce motion and forces. Single
molecule experiments have led to a precise description of how a motor works. Under most …

Transport efficiency of membrane-anchored kinesin-1 motors depends on motor density and diffusivity

R Grover, J Fischer, FW Schwarz… - Proceedings of the …, 2016 - National Acad Sciences
In eukaryotic cells, membranous vesicles and organelles are transported by ensembles of
motor proteins. These motors, such as kinesin-1, have been well characterized in vitro as …

Robust transport by multiple motors with nonlinear force–velocity relations and stochastic load sharing

A Kunwar, A Mogilner - Physical biology, 2010 - iopscience.iop.org
Transport by processive molecular motors plays an important role in many cell biological
phenomena. In many cases, motors work together to transport cargos in the cell, so it is …

Phospholipid membranes as chemically and functionally tunable materials

D Huster, S Maiti, A Herrmann - Advanced Materials, 2024 - Wiley Online Library
The sheet‐like lipid bilayer is the fundamental structural component of all cell membranes.
Its building blocks are phospholipids and cholesterol. Their amphiphilic structure …