Tasks, techniques, and tools for genomic data visualization
Genomic data visualization is essential for interpretation and hypothesis generation as well
as a valuable aid in communicating discoveries. Visual tools bridge the gap between …
as a valuable aid in communicating discoveries. Visual tools bridge the gap between …
Computational analysis and prediction of lysine malonylation sites by exploiting informative features in an integrative machine-learning framework
As a newly discovered post-translational modification (PTM), lysine malonylation (Kmal)
regulates a myriad of cellular processes from prokaryotes to eukaryotes and has important …
regulates a myriad of cellular processes from prokaryotes to eukaryotes and has important …
Post-translational modifications reshape the antigenic landscape of the MHC I immunopeptidome in tumors
A Kacen, A Javitt, MP Kramer, D Morgenstern… - Nature …, 2023 - nature.com
Post-translational modification (PTM) of antigens provides an additional source of
specificities targeted by immune responses to tumors or pathogens, but identifying antigen …
specificities targeted by immune responses to tumors or pathogens, but identifying antigen …
PhosphoSitePlus, 2014: mutations, PTMs and recalibrations
PV Hornbeck, B Zhang, B Murray… - Nucleic acids …, 2015 - academic.oup.com
Abstract PhosphoSitePlus®(PSP, http://www. phosphosite. org/), a knowledgebase
dedicated to mammalian post-translational modifications (PTMs), contains over 330 000 non …
dedicated to mammalian post-translational modifications (PTMs), contains over 330 000 non …
m5U-SVM: identification of RNA 5-methyluridine modification sites based on multi-view features of physicochemical features and distributed representation
Abstract Background RNA 5-methyluridine (m5U) modifications are obtained by methylation
at the C5 position of uridine catalyzed by pyrimidine methylation transferase, which is …
at the C5 position of uridine catalyzed by pyrimidine methylation transferase, which is …
In Silico Approach for Predicting Toxicity of Peptides and Proteins
Background Over the past few decades, scientific research has been focused on developing
peptide/protein-based therapies to treat various diseases. With the several advantages over …
peptide/protein-based therapies to treat various diseases. With the several advantages over …
Designing of interferon-gamma inducing MHC class-II binders
Background The generation of interferon-gamma (IFN-γ) by MHC class II activated CD4+ T
helper cells play a substantial contribution in the control of infections such as caused by …
helper cells play a substantial contribution in the control of infections such as caused by …
PhosphoSitePlus: a comprehensive resource for investigating the structure and function of experimentally determined post-translational modifications in man and …
PV Hornbeck, JM Kornhauser, S Tkachev… - Nucleic acids …, 2012 - academic.oup.com
Abstract PhosphoSitePlus (http://www. phosphosite. org) is an open, comprehensive,
manually curated and interactive resource for studying experimentally observed post …
manually curated and interactive resource for studying experimentally observed post …
Deep-Kcr: accurate detection of lysine crotonylation sites using deep learning method
As a newly discovered protein posttranslational modification, histone lysine crotonylation
(Kcr) involved in cellular regulation and human diseases. Various proteomics technologies …
(Kcr) involved in cellular regulation and human diseases. Various proteomics technologies …
Lag phase is a distinct growth phase that prepares bacteria for exponential growth and involves transient metal accumulation
MD Rolfe, CJ Rice, S Lucchini, C Pin… - Journal of …, 2012 - Am Soc Microbiol
Lag phase represents the earliest and most poorly understood stage of the bacterial growth
cycle. We developed a reproducible experimental system and conducted functional genomic …
cycle. We developed a reproducible experimental system and conducted functional genomic …