Overview of epidemiology and contribution of obesity and body fat distribution to cardiovascular disease: an update

ME Piché, P Poirier, I Lemieux, JP Després - Progress in cardiovascular …, 2018 - Elsevier
Obesity is recognized as a heterogeneous condition in which individuals with similar body
mass index may have distinct metabolic and cardiovascular risk profiles. Susceptibility to …

Healthy Weight and Obesity Prevention: JACC Health Promotion Series

CJ Lavie, D Laddu, R Arena, FB Ortega… - Journal of the American …, 2018 - jacc.org
Overweight and obesity have reached epidemic levels in the United States and worldwide,
and this has contributed to substantial cardiovascular and other health risks. However …

Epidemiology of hepatocellular carcinoma: target population for surveillance and diagnosis

A Tang, O Hallouch, V Chernyak, A Kamaya… - Abdominal …, 2018 - Springer
Hepatocellular carcinoma (HCC) is the sixth most common cancer and the second leading
cause of cancer mortality worldwide. Incidence rates of liver cancer vary widely between …

Clinical diabetic cardiomyopathy: a two-faced disease with restrictive and dilated phenotypes

PM Seferović, WJ Paulus - European heart journal, 2015 - academic.oup.com
Diabetes mellitus-related cardiomyopathy (DMCMP) was originally described as a dilated
phenotype with eccentric left ventricular (LV) remodelling and systolic LV dysfunction …

[HTML][HTML] Epidemiology, pathophysiology, diagnosis and treatment of heart failure in diabetes

JJ Park - Diabetes & metabolism journal, 2021 - synapse.koreamed.org
The cardiovascular disease continuum begins with risk factors such as diabetes mellitus
(DM), progresses to vasculopathy and myocardial dysfunction, and finally ends with …

Obesity and cardiovascular disease: a risk factor or a risk marker?

T Mandviwala, U Khalid, A Deswal - Current atherosclerosis reports, 2016 - Springer
In the USA, 69% of adults are either overweight or obese and 35% are obese. Obesity is
associated with an increased incidence of various cardiovascular disorders. Obesity is a risk …

Effects of obesity on cardiovascular hemodynamics, cardiac morphology, and ventricular function

MA Alpert, J Omran, BP Bostick - Current obesity reports, 2016 - Springer
Obesity produces a variety of hemodynamic alterations that may cause changes in cardiac
morphology which predispose to left and right ventricular dysfunction. Various …

Molecular distinction between physiological and pathological cardiac hypertrophy: experimental findings and therapeutic strategies

BC Bernardo, KL Weeks, L Pretorius… - Pharmacology & …, 2010 - Elsevier
Cardiac hypertrophy can be defined as an increase in heart mass. Pathological cardiac
hypertrophy (heart growth that occurs in settings of disease, eg hypertension) is a key risk …

Mechanisms linking obesity with cardiovascular disease

LF Van Gaal, IL Mertens, CE De Block - Nature, 2006 - nature.com
Obesity increases the risk of cardiovascular disease and premature death. Adipose tissue
releases a large number of bioactive mediators that influence not only body weight …

Endothelial dysfunction in obesity

A Engin - Obesity and lipotoxicity, 2017 - Springer
Chronic inflammatory state in obesity causes dysregulation of the endocrine and paracrine
actions of adipocyte-derived factors, which disrupt vascular homeostasis and contribute to …