Peripheral quantitative computed tomography provides an automatical scan analysis of
trabecular and cortical bone compartments, calculating not only their bone mineral density …

Glucocorticoids inhibit osteoblasts through multiple mechanisms, which results in significant
reductions in bone formation. The growing skeleton may be especially vulnerable to adverse …

Objective To identify the mediator responsible for the impact of chronic inflammation on
skeletal development in children (bone loss, defective peak bone mass accrual, stunted …

High fat diets can have detrimental effects on the skeleton as well as cause intestinal
dysbiosis. Exercise prevents high fat (HF) diet-induced obesity and also improves bone …

Background & Aims: Although patients with inflammatory bowel disease (IBD) have reduced
bone mass, there is controversy whether there is an increased risk of fracture. This study …

purpose. The response of retinal ganglion cells (RGCs) to ocular pressure in glaucoma
likely involves signals from astrocytes and microglia. How glia-derived factors influence …

BACKGROUND & AIMS: The impact of childhood Crohn's disease (CD) and its therapies on
volumetric bone mineral density (vBMD), bone structure, and muscle mass have not been …

Current evidence points to suboptimal bone health in children and adolescents with
inflammatory bowel disease (IBD) when compared with their healthy peers. This …

Background & Aims: Bone loss is a common complication of human inflammatory bowel
disease (IBD), but its mechanisms are not understood completely. We investigated bone …

Aims To assess bone mineral density (BMD) in children with Crohn's disease (CD) and
ulcerative colitis (UC) and to investigate the role of inflammation and steroids on BMD …