Chronic pancreatitis and pancreatic cancer risk: a systematic review and meta-analysis

J Kirkegård, FV Mortensen… - Official journal of the …, 2017 - journals.lww.com
Chronic pancreatitis is a putative risk factor for pancreatic cancer. The aim of this study was
to examine the magnitude and temporality of this association. We searched MEDLINE and …

Stromal biology and therapy in pancreatic cancer: a changing paradigm

A Neesse, H Algül, DA Tuveson, TM Gress - Gut, 2015 - gut.bmj.com
Pancreatic ductal adenocarcinoma (PDA) exhibits one of the poorest prognosis of all solid
tumours and poses an unsolved problem in cancer medicine. Despite the recent success of …

Pancreas—its functions, disorders, and physiological impact on the mammals' organism

M Karpińska, M Czauderna - Frontiers in physiology, 2022 - frontiersin.org
This review aimed to analyze the scientific literature on pancreatic diseases (especially
exocrine pancreatic insufficiency). This review also describes the correlation between the …

Pancreatic ductal adenocarcinoma: Epidemiology and risk factors

J Ushio, A Kanno, E Ikeda, K Ando, H Nagai, T Miwata… - Diagnostics, 2021 - mdpi.com
The number of new cases of pancreatic ductal adenocarcinoma is increasing with a
cumulative total of 495,773 cases worldwide, making it the fourteenth most common …

Acute pancreatitis and pancreatic cancer risk: a nationwide matched-cohort study in Denmark

J Kirkegård, D Cronin-Fenton, U Heide-Jørgensen… - Gastroenterology, 2018 - Elsevier
Background & Aims Acute pancreatitis may be a risk factor for pancreatic cancer; however,
findings from studies on this association are conflicting. We investigated the association …

[HTML][HTML] Key players in pancreatic cancer-stroma interaction: Cancer-associated fibroblasts, endothelial and inflammatory cells

MFB Nielsen, MB Mortensen… - World journal of …, 2016 - ncbi.nlm.nih.gov
Pancreatic cancer (PC) is the most aggressive type of common cancers, and in 2014, nearly
40000 patients died from the disease in the United States. Pancreatic ductal …

Epidemiology of recurrent acute and chronic pancreatitis: similarities and differences

JD Machicado, D Yadav - Digestive diseases and sciences, 2017 - Springer
Emerging data in the past few years suggest that acute, recurrent acute (RAP), and chronic
pancreatitis (CP) represent a disease continuum. This review discusses the similarities and …

S3-leitlinie pankreatitis–leitlinie der deutschen gesellschaft für gastroenterologie, verdauungs-und stoffwechselkrankheiten (DGVS)–september 2021–AWMF …

G Beyer, A Hoffmeister, P Michl… - Zeitschrift für …, 2022 - thieme-connect.com
Diese Leitlinie umfasst erstmals die akute wie auch die chronische Pankreatitis, um so
Übergänge der beiden ehemals getrennt wahrgenommenen Krankheitsbilder gemäß einem …

[HTML][HTML] Piezo1-mediated stellate cell activation causes pressure-induced pancreatic fibrosis in mice

SM Swain, JMJ Romac, SR Vigna, RA Liddle - JCI insight, 2022 - ncbi.nlm.nih.gov
Pancreatic fibrosis is a complication of chronic pancreatitis and is a prominent feature of
pancreatic cancer. Pancreatic fibrosis is commonly observed in patients with prolonged …

The gut microbiome in patients with chronic pancreatitis is characterized by significant dysbiosis and overgrowth by opportunistic pathogens

F Frost, FU Weiss, M Sendler… - Clinical and …, 2020 - journals.lww.com
METHODS: Patients with clinical and imaging evidence of CP (n= 51) were prospectively
recruited and compared with twice the number of nonpancreatic disease controls matched …