The first human tumor virus was discovered in the middle of the last century by Anthony
Epstein, Bert Achong and Yvonne Barr in African pediatric patients with Burkitt's lymphoma …

Cancer progression and metastasis are processes that involve significant cellular changes.
Many of these changes include alterations in the activity of the Rho GTPase family of …

Cancer stem-like cells are thought to contribute to tumor recurrence. The anthrax toxin
receptor 1 (ANTXR1) has been identified as a functional biomarker of normal stem cells and …

Breast cancer is one of the most frequently diagnosed malignancies, and despite extensive
molecular and cellular research, the mortality rate remains high. Preclinical testing of new …

Rho GTPases activated in cancer cells drive proliferation, migration, and metastasis. Thus,
RhoGAP proteins, which negatively regulate Rho GTPases, are generally thought to function …

Host cells respond to viral infections by activating immune response genes that are not only
involved in inflammation, but may also predispose cells to cancerous transformation. One …

A Human Betaretrovirus (HBRV) has been identified in humans, dating as far back as about
4500 years ago, with a high probability of it being acquired by our species around 10,000 …

Mouse mammary tumor virus (MMTV), which was discovered as a milk-transmitted,
infectious, cancer-inducing agent in the 1930s, has been used as an animal model for the …

The most common events in breast cancer (BC) involve chromosome arm losses and gains.
Here we describe identification of 1089 gene-centric common insertion sites (gCIS) from …

Upon cell infection, some viruses integrate their genome into the host chromosome, either
as part of their life cycle (such as retroviruses), or incidentally. While possibly promoting long …