From strings to signals: Unraveling the impact of miRNAs on diagnosis, and progression of colorectal cancer
OA Mohammed - Pathology-Research and Practice, 2023 - Elsevier
Colorectal cancer (CRC) stands as the third most prevalent ailment globally and represents
the primary cause of mortality associated with cancer. Significant advancements have been …
the primary cause of mortality associated with cancer. Significant advancements have been …
The potential relevance of long non-coding RNAs in colorectal cancer pathogenesis and treatment: A review focus on signaling pathways
Colorectal cancer (CRC) is one of the most frequent cancers in incidence and mortality.
Despite advances in cancer biology, molecular genetics, and targeted treatments, CRC …
Despite advances in cancer biology, molecular genetics, and targeted treatments, CRC …
Unveiling the therapeutic potential of exogenous β-hydroxybutyrate for chronic colitis in rats: Novel insights on autophagy, apoptosis, and pyroptosis
R Abdelhady, S Saber… - Frontiers in …, 2023 - frontiersin.org
Ulcerative colitis (UC) is a chronic relapsing inflammatory disease of the colorectal area that
demonstrates a dramatically increasing incidence worldwide. This study provides novel …
demonstrates a dramatically increasing incidence worldwide. This study provides novel …
Alvespimycin exhibits potential anti-TGF-β signaling in the setting of a proteasome activator in rats with bleomycin-induced pulmonary fibrosis: a promising novel …
Idiopathic pulmonary fibrosis (IPF) is an irreversible and life-threatening lung disease of
unknown etiology presenting only a few treatment options. TGF-β signaling orchestrates a …
unknown etiology presenting only a few treatment options. TGF-β signaling orchestrates a …
[HTML][HTML] Innovative challenge for the inhibition of hepatocellular carcinoma progression by combined targeting of HSP90 and STAT3/HIF-1α signaling
S Saber, EE Abd El-Fattah, AM Abdelhamid… - Biomedicine & …, 2023 - Elsevier
Hepatocellular carcinoma (HCC) is the third foremost cause of cancer-related deaths. HCC
has a very bad prognosis because it is asymptomatic in the early stages, resulting in a late …
has a very bad prognosis because it is asymptomatic in the early stages, resulting in a late …
Itraconazole halts hepatocellular carcinoma progression by modulating sonic hedgehog signaling in rats: A novel therapeutic approach
Liver cancer stands as the fourth leading global cause of death, and its prognosis remains
grim due to the limited effectiveness of current medical interventions. Among the various …
grim due to the limited effectiveness of current medical interventions. Among the various …
[HTML][HTML] Diacetylrhein, an anthraquinone antiarthritic agent, suppresses dextran sodium sulfate-induced inflammation in rats: A possible mechanism for a protective …
Ulcerative colitis (UC) is a chronic inflammatory life-threatening and premalignant disorder
with no cure that even might end up with surgical removal of a large section or even all of the …
with no cure that even might end up with surgical removal of a large section or even all of the …
Oxysophocarpine suppresses TRAF6 level to ameliorate oxidative stress and inflammatory factors secretion in mice with dextran sulphate sodium (DSS) induced …
C Liu, R Wang, X Jiao, J Zhang, C Zhang… - Microbial Pathogenesis, 2023 - Elsevier
Purpose Ulcerative colitis is an inflammation-related disease with a high recurrence risk.
Oxysophocarpine (OSC) is a traditional Chinese medicine isolated from legumes and exerts …
Oxysophocarpine (OSC) is a traditional Chinese medicine isolated from legumes and exerts …
The role of organosulfur compounds as Nrf2 activators and their antioxidant effects
Nuclear factor erythroid 2-related factor 2 (Nrf2) signaling has become a key pathway for
cellular regulation against oxidative stress and inflammation, and therefore an attractive …
cellular regulation against oxidative stress and inflammation, and therefore an attractive …
Alogliptin exhibits multifaceted effects in thioacetamide-insulted rats: a novel approach to combating hepatic inflammation and fibrogenesis
OA Mohammed - Pathology-Research and Practice, 2023 - Elsevier
Hepatic fibrosis arising from chronic liver injury is characterized by dysregulated healing,
including hepatic stellate cell activation and excessive deposition of extracellular matrix …
including hepatic stellate cell activation and excessive deposition of extracellular matrix …