Abstract Alzheimer's disease (AD), the most common cause of dementia, results in a
sustained decline in cognition. There are currently few effective disease modifying therapies …

Executive summary The number of older people, including those living with dementia, is
rising, as younger age mortality declines. However, the age-specific incidence of dementia …

Sleep dysregulation is a feature of dementia but it remains unclear whether sleep duration
prior to old age is associated with dementia incidence. Using data from 7959 participants of …

The circadian clock evolved in diverse organisms to integrate external environmental
changes and internal physiology. The clock endows the host with temporal precision and …

Executive summary The 2024 update of the Lancet Commission on dementia provides new
hopeful evidence about dementia prevention, intervention, and care. As people live longer …

As we age, we experience changes in our nighttime sleep and daytime wakefulness.
Individuals afflicted with Alzheimer's disease (AD) can develop sleep problems even before …

Alzheimer's disease (AD) is associated with memory impairment and altered peripheral
metabolism. Mounting evidence indicates that abnormal signaling in a brain-periphery …

In mammals, a central circadian clock, located in the suprachiasmatic nuclei (SCN) of the
hypothalamus, tunes the innate circadian physiological rhythms to the ambient 24 h light …

In this paper, we explore the utility of resting-state EEG measures as potential biomarkers for
the detection and assessment of cognitive decline in mild cognitive impairment (MCI) and …

Alzheimer's disease and related dementias (ADRDs) are a global crisis facing the aging
population and society as a whole. With the numbers of people with ADRDs predicted to rise …