Cancer/testis antigens: from serology to mRNA cancer vaccine
Cancer/testis antigens (CTAs) are a group of tumor antigens expressed in numerous cancer
tissues, as well as in the testis and placental tissues. There are over 200 CTAs supported by …
tissues, as well as in the testis and placental tissues. There are over 200 CTAs supported by …
Cancer testis antigen subfamilies: Attractive targets for therapeutic vaccine
S Ren, Z Zhang, M Li, D Wang… - International …, 2023 - spandidos-publications.com
Cancer‑testis antigen (CTA) is a well‑accepted optimal target library for cancer diagnosis
and treatment. Most CTAs are located on the X chromosome and aggregate into large gene …
and treatment. Most CTAs are located on the X chromosome and aggregate into large gene …
Anti-cancer auto-antibodies: Roles, applications and open issues
Simple Summary Cancer is one of the main causes of death worldwide and early detection
is crucial for effective treatment. Scientists have therefore focused on the identification of …
is crucial for effective treatment. Scientists have therefore focused on the identification of …
The paradox of cancer genes in non-malignant conditions: implications for precision medicine
JJ Adashek, S Kato, SM Lippman, R Kurzrock - Genome medicine, 2020 - Springer
Next-generation sequencing has enabled patient selection for targeted drugs, some of
which have shown remarkable efficacy in cancers that have the cognate molecular …
which have shown remarkable efficacy in cancers that have the cognate molecular …
[HTML][HTML] Sperm proteins and cancer‐testis antigens are released by the seminiferous tubules in mice and men
L O'Donnell, D Rebourcet, LF Dagley, R Sgaier… - The FASEB …, 2021 - ncbi.nlm.nih.gov
Sperm develop from puberty in the seminiferous tubules, inside the blood‐testis barrier to
prevent their recognition as “non‐self” by the immune system, and it is widely assumed that …
prevent their recognition as “non‐self” by the immune system, and it is widely assumed that …
Development of autoantibody signatures for common cancers
M Kobayashi, H Katayama, JF Fahrmann… - Seminars in …, 2020 - Elsevier
A humoral immune response in the form of autoantibodies to tumor antigens occurs early
during tumor development. Identification of antigens that induce an autoantibody response …
during tumor development. Identification of antigens that induce an autoantibody response …
Discovering panel of autoantibodies for early detection of lung cancer based on focused protein array
D Jiang, X Zhang, M Liu, Y Wang, T Wang… - Frontiers in …, 2021 - frontiersin.org
Substantial studies indicate that autoantibodies to tumor-associated antigens (TAAbs) arise
in early stage of lung cancer (LC). However, since single TAAbs as non-invasive biomarkers …
in early stage of lung cancer (LC). However, since single TAAbs as non-invasive biomarkers …
Comprehensive analysis of the carcinogenic process, tumor microenvironment, and drug response in HPV-positive cancers
Human papillomavirus (HPV) is a common virus, and about 5% of all cancers worldwide is
caused by persistent high-risk HPV infections. Here, we reported a comprehensive analysis …
caused by persistent high-risk HPV infections. Here, we reported a comprehensive analysis …
The diagnostic efficiency of seven autoantibodies in lung cancer
H Huang, W Luo, Y Ni, S Sun, C Wang… - European Journal of …, 2020 - journals.lww.com
This study aimed to evaluate the diagnostic efficacy of seven autoantibodies in all lung
cancer, lung adenocarcinoma, lung squamous cell carcinoma and early-stage lung cancer …
cancer, lung adenocarcinoma, lung squamous cell carcinoma and early-stage lung cancer …
Identification of novel autoantibodies based on the human proteomic chips and evaluation of their performance in the detection of gastric cancer
C Cui, Y Duan, C Qiu, P Wang, G Sun, H Ye… - Frontiers in …, 2021 - frontiersin.org
Autoantibodies against tumor-associated antigens (TAAbs) can be used as potential
biomarkers in the detection of cancer. Our study aims to identify novel TAAbs for gastric …
biomarkers in the detection of cancer. Our study aims to identify novel TAAbs for gastric …