Metastasis, the leading cause of cancer deaths, is an intricate process involving many
important tumor and stromal proteins that have yet to be fully defined. This review discusses …

Connective Tissue Growth Factor/Cysteine- Rich 61/Nephroblastoma Overexpressed (CCN)
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Connective tissue growth factor (CTGF, CCN2) is a secreted protein with major roles in
angiogenesis, chondrogenesis, osteogenesis, tissue repair, cancer and fibrosis. It is a …

Connective tissue growth factor (CTGF) is a member of the recently described CCN gene
family which contains CTGF itself, cyr61, nov, elm1, Cop1, and WISP-3. CTGF is …

Connective tissue growth factor: Potential role in glomerulosclerosis and tubulointerstitial
fibrosis. Transforming growth factor beta (TGF-β) is a pivotal driver of glomerulosclerosis and …

To gain insight into the role of the CCN genes in human breast carcinomas, we quantified
connective tissue growth factor (CTGF), WISP-1, CYR61, and human NOV (NOVH) mRNA …

Connective tissue growth factor (CTGF/CCN2) is a highly profibrogenic molecule which is
overexpressed in many fibrotic lesions, including those of the liver. CTGF/CCN2 is …

The biological properties of CCN proteins include stimulation of cell proliferation, migration,
and adhesion, as well as angiogenesis and tumorigenesis. We quantified CYR61, CTGF …

Abstract Background The Hippo pathway is widely considered to inhibit cell growth and play
an important role in regulating the size of organs. However, recent studies have shown that …

Purpose: Differential cDNA library screening was performed on 7 human lung
adenocarcinomas and 7 human lung squamous cell carcinomas and their corresponding …