The lung is the primary site of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2)-induced immunopathology whereby the virus enters the host cells by binding to …

Organoids represent one of the most important advancements in the field of stem cells
during the past decade. They are three-dimensional in vitro culturing models that originate …

We present a multiomic cell atlas of human lung development that combines single-cell RNA
and ATAC sequencing, high-throughput spatial transcriptomics, and single-cell imaging …

The human lung plays vital roles in respiration, host defense, and basic physiology. Recent
technological advancements such as single-cell RNA sequencing and genetic lineage …

Dynein-decorated doublet microtubules (DMTs) are critical components of the oscillatory
molecular machine of cilia, the axoneme, and have luminal surfaces patterned periodically …

The heterogeneous cellular microenvironment of human airway chronic inflammatory
diseases, including chronic rhinosinusitis (CRS) and asthma, is still poorly understood …

Life-long reconstitution of a tissue's resident stem cell compartment with engrafted cells has
the potential to durably replenish organ function. Here, we demonstrate the engraftment of …

The cilium-centrosome complex contains triplet, doublet, and singlet microtubules. The
lumenal surfaces of each microtubule within this diverse array are decorated by microtubule …

Many human phenotypes are impossible to recapitulate in model organisms or immortalized
human cell lines. Induced pluripotent stem cells (iPSCs) offer a way to study disease …

The mammalian lung epithelium is composed of a wide array of specialized cells that have
adapted to survive environmental exposure and perform the tasks necessary for respiration …