Autophagy, as a type II programmed cell death, plays crucial roles with autophagy-related
(ATG) proteins in cancer. Up to now, the dual role of autophagy both in cancer progression …

Autophagosomes are double-membrane vesicles newly formed during autophagy to engulf
a wide range of intracellular material and transport this autophagic cargo to lysosomes (or …

Autophagy-dependent cell death can be defined as cell demise that has a strict requirement
of autophagy. Although autophagy often accompanies cell death following many toxic …

Many biomolecules undergo liquid–liquid phase separation to form liquid-like condensates
that mediate diverse cellular functions,. Autophagy is able to degrade such condensates …

The selective clearance of organelles by autophagy is critical for the regulation of cellular
homeostasis in organisms from yeast to humans. Removal of damaged organelles clears …

Autophagy is the major cellular pathway to degrade dysfunctional organelles and protein
aggregates. Autophagy is particularly important in neurons, which are terminally …

Macroautophagy/autophagy is an evolutionarily conserved cellular degradation process that
targets cytoplasmic materials including cytosol, macromolecules and unwanted organelles …

Autophagy is a lysosome-dependent cellular degradation program that responds to a variety
of environmental and cellular stresses. It is an evolutionarily well-conserved and essential …

Autophagy is the process of cellular self-eating by a double-membrane organelle, the
autophagosome. A range of signaling processes converge on two protein complexes to …

Alzheimer's disease (AD) is the most common cause of progressive dementia in the elderly.
It is characterized by a progressive and irreversible loss of cognitive abilities and formation …