Tumor microenvironment: barrier or opportunity towards effective cancer therapy

A Tiwari, R Trivedi, SY Lin - Journal of biomedical science, 2022 - Springer
Tumor microenvironment (TME) is a specialized ecosystem of host components, designed
by tumor cells for successful development and metastasis of tumor. With the advent of 3D …

3D cell culture systems: tumor application, advantages, and disadvantages

O Habanjar, M Diab-Assaf, F Caldefie-Chezet… - International journal of …, 2021 - mdpi.com
The traditional two-dimensional (2D) in vitro cell culture system (on a flat support) has long
been used in cancer research. However, this system cannot be fully translated into clinical …

Dynamic and reconfigurable materials from reversible network interactions

MJ Webber, MW Tibbitt - Nature Reviews Materials, 2022 - nature.com
Polymer materials provide solutions to some of the most pressing environmental,
manufacturing and health-care challenges. Traditional thermoplastic and thermoset …

Polymeric tissue adhesives

S Nam, D Mooney - Chemical reviews, 2021 - ACS Publications
Polymeric tissue adhesives provide versatile materials for wound management and are
widely used in a variety of medical settings ranging from minor to life-threatening tissue …

Advances in 3D bioprinting of tissues/organs for regenerative medicine and in-vitro models

P Jain, H Kathuria, N Dubey - Biomaterials, 2022 - Elsevier
Tissue/organ shortage is a major medical challenge due to donor scarcity and patient
immune rejections. Furthermore, it is difficult to predict or mimic the human disease condition …

Electroactive biomaterials and systems for cell fate determination and tissue regeneration: design and applications

Z Liu, X Wan, ZL Wang, L Li - Advanced Materials, 2021 - Wiley Online Library
During natural tissue regeneration, tissue microenvironment and stem cell niche including
cell–cell interaction, soluble factors, and extracellular matrix (ECM) provide a train of …

[HTML][HTML] 3D printing of hydrogels: Rational design strategies and emerging biomedical applications

J Li, C Wu, PK Chu, M Gelinsky - Materials Science and Engineering: R …, 2020 - Elsevier
Abstract 3D printing alias additive manufacturing can transform 3D virtual models created by
computer-aided design (CAD) into physical 3D objects in a layer-by-layer manner …

[HTML][HTML] 3D in vitro model (R) evolution: unveiling tumor–stroma interactions

J Rodrigues, MA Heinrich, LM Teixeira, J Prakash - Trends in cancer, 2021 - cell.com
The complex microenvironment in which malignant tumor cells grow is crucial for cancer
progression. The physical and biochemical characteristics of this niche are involved in …

Hydrogel microparticles for biomedical applications

AC Daly, L Riley, T Segura, JA Burdick - Nature Reviews Materials, 2020 - nature.com
Hydrogel microparticles (HMPs) are promising for biomedical applications, ranging from the
therapeutic delivery of cells and drugs to the production of scaffolds for tissue repair and …

Volumetric additive manufacturing of pristine silk-based (bio) inks

M Xie, L Lian, X Mu, Z Luo… - Nature …, 2023 - nature.com
Volumetric additive manufacturing (VAM) enables fast photopolymerization of three-
dimensional constructs by illuminating dynamically evolving light patterns in the entire build …