Detecting RNA modifications in the epitranscriptome: predict and validate
RNA modifications are emerging players in the field of post-transcriptional regulation of
gene expression, and are attracting a comparable degree of research interest to DNA and …
gene expression, and are attracting a comparable degree of research interest to DNA and …
N6-Methyl-Adenosine (m6A) in RNA: An Old Modification with A Novel Epigenetic Function
Abstract N6-methyl-adenosine (m6A) is one of the most common and abundant
modifications on RNA molecules present in eukaryotes. However, the biological significance …
modifications on RNA molecules present in eukaryotes. However, the biological significance …
N 6-methyladenosine alters RNA structure to regulate binding of a low-complexity protein
Abstract N 6-methyladenosine (m6A) is the most abundant internal modification in
eukaryotic messenger RNA (mRNA), and affects almost every stage of the mRNA life cycle …
eukaryotic messenger RNA (mRNA), and affects almost every stage of the mRNA life cycle …
The dynamic N1-methyladenosine methylome in eukaryotic messenger RNA
D Dominissini, S Nachtergaele, S Moshitch-Moshkovitz… - Nature, 2016 - nature.com
Gene expression can be regulated post-transcriptionally through dynamic and reversible
RNA modifications. A recent noteworthy example is N 6-methyladenosine (m6A), which …
RNA modifications. A recent noteworthy example is N 6-methyladenosine (m6A), which …
Regulation of co-transcriptional pre-mRNA splicing by m6A through the low-complexity protein hnRNPG
Summary N 6-methyladenosine (m 6 A) modification occurs co-transcriptionally and impacts
pre-mRNA processing; however, the mechanism of co-transcriptional m 6 A-dependent …
pre-mRNA processing; however, the mechanism of co-transcriptional m 6 A-dependent …
Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq
D Dominissini, S Moshitch-Moshkovitz, S Schwartz… - Nature, 2012 - nature.com
An extensive repertoire of modifications is known to underlie the versatile coding, structural
and catalytic functions of RNA, but it remains largely uncharted territory. Although …
and catalytic functions of RNA, but it remains largely uncharted territory. Although …
m6A RNA methylation is regulated by microRNAs and promotes reprogramming to pluripotency
Summary N 6-methyladenosine (m 6 A) has been recently identified as a conserved
epitranscriptomic modification of eukaryotic mRNAs, but its features, regulatory mechanisms …
epitranscriptomic modification of eukaryotic mRNAs, but its features, regulatory mechanisms …
Transcriptome-wide mapping of N6-methyladenosine by m6A-seq based on immunocapturing and massively parallel sequencing
D Dominissini, S Moshitch-Moshkovitz… - Nature protocols, 2013 - nature.com
Abstract N 6-methyladenosine–sequencing (m6A-seq) is an immunocapturing approach for
the unbiased transcriptome-wide localization of m6A in high resolution. To our knowledge …
the unbiased transcriptome-wide localization of m6A in high resolution. To our knowledge …
High‐Resolution N6‐Methyladenosine (m6A) Map Using Photo‐Crosslinking‐Assisted m6A Sequencing
Abstract N6‐methyladenosine (m6A) is an abundant internal modification in eukaryotic
mRNA and plays regulatory roles in mRNA metabolism. However, methods to precisely …
mRNA and plays regulatory roles in mRNA metabolism. However, methods to precisely …
Probing N6-methyladenosine RNA modification status at single nucleotide resolution in mRNA and long noncoding RNA
N 6-methyladenosine (m6A) is the most abundant modification in mammalian mRNA and
long noncoding RNA (lncRNA). Recent discoveries of two m6A demethylases and cell-type …
long noncoding RNA (lncRNA). Recent discoveries of two m6A demethylases and cell-type …