Prostate cancer radiogenomics—from imaging to molecular characterization
M Ferro, O de Cobelli, MD Vartolomei… - International Journal of …, 2021 - mdpi.com
Radiomics and genomics represent two of the most promising fields of cancer research,
designed to improve the risk stratification and disease management of patients with prostate …
designed to improve the risk stratification and disease management of patients with prostate …
14–3-3ε: a protein with complex physiology function but promising therapeutic potential in cancer
Y Zhang, M Yan, Y Yu, J Wang, Y Jiao, M Zheng… - Cell Communication and …, 2024 - Springer
Over the past decade, the role of the 14–3-3 protein has received increasing interest. Seven
subtypes of 14–3-3 proteins exhibit high homology; however, each subtype maintains its …
subtypes of 14–3-3 proteins exhibit high homology; however, each subtype maintains its …
Long noncoding RNAs and circular RNAs regulate AKT and its effectors to control cell functions of cancer cells
AKT serine-threonine kinase (AKT) and its effectors are essential for maintaining cell
proliferation, apoptosis, autophagy, endoplasmic reticulum (ER) stress, mitochondrial …
proliferation, apoptosis, autophagy, endoplasmic reticulum (ER) stress, mitochondrial …
Annotation and functional characterization of long noncoding RNAs deregulated in pancreatic adenocarcinoma
VF da Paixão, OJ Sosa, DV da Silva Pellegrina… - Cellular Oncology, 2022 - Springer
Purpose Transcriptome analysis of pancreatic ductal adenocarcinoma (PDAC) has been
useful to identify gene expression changes that sustain malignant phenotypes. Yet, most …
useful to identify gene expression changes that sustain malignant phenotypes. Yet, most …
N6-methyladenosine modified lncRNAs signature for stratification of biochemical recurrence in prostate cancer
Y Liang, W Yin, Z Cai, H Luo, Q Liu, C Zhong, J Chen… - Human Genetics, 2024 - Springer
Nonmutational epigenetic reprogramming is a crucial mechanism contributing to the
pronounced heterogeneity of prostate cancer (PCa). Among these mechanisms, N6 …
pronounced heterogeneity of prostate cancer (PCa). Among these mechanisms, N6 …
Importance of long non-coding RNAs in the pathogenesis, diagnosis, and treatment of prostate cancer
Long non-coding RNAs (lncRNAs) are regulatory transcripts with essential roles in the
pathogenesis of almost all types of cancers, including prostate cancer. They can act as …
pathogenesis of almost all types of cancers, including prostate cancer. They can act as …
miR-449a Repression Leads to Enhanced NOTCH Signaling in TMPRSS2:ERG Fusion Positive Prostate Cancer Cells
S Bauer, L Ratz, D Heckmann-Nötzel, A Kaczorowski… - Cancers, 2021 - mdpi.com
Simple Summary The reason for the frequent presence of the TMPRSS2: ERG (T2E) gene
fusion in prostate cancer (PCa) is not fully understood. We were interested in investigating …
fusion in prostate cancer (PCa) is not fully understood. We were interested in investigating …
Histone methyltransferase SUV39H2 regulates apoptosis and chemosensitivity in prostate cancer through AKT/FOXO signaling pathway
D Sun, J Guo, W Liang, Y Chen, S Wei, A Li, L Wang… - Medical Oncology, 2024 - Springer
Prostate cancer (PCa) is one of the most common malignant tumors that exhibit both
chemoresistance and recurrence. SUV39H2 is highly expressed in many types of human …
chemoresistance and recurrence. SUV39H2 is highly expressed in many types of human …
Interactions between 14-3-3 Proteins and Actin Cytoskeleton and Its Regulation by microRNAs and Long Non-Coding RNAs in Cancer
J Aseervatham - Endocrines, 2022 - mdpi.com
14-3-3s are a family of structurally similar proteins that bind to phosphoserine or
phosphothreonine residues, forming the central signaling hub that coordinates or integrates …
phosphothreonine residues, forming the central signaling hub that coordinates or integrates …
[HTML][HTML] miR-196b 靶向ERG 促进肺腺癌的增殖和迁移
刘邦卿， 李剑锋， 刘晓辉， 张劲男… - 昆明医科大学 …, 2023 - kyxuebao.kmmu.edu.cn
目的探究miR-196b 影响肺腺癌(lung adenocarcinoma, LUAD) 进展的机制. 方法通过TCGA
数据库分析miR-196b 在LUAD 组织中的表达水平, 利用TargetScan 预测其下游靶基因并用双 …
数据库分析miR-196b 在LUAD 组织中的表达水平, 利用TargetScan 预测其下游靶基因并用双 …