[HTML][HTML] Natural therapeutics and nutraceuticals for lung diseases: traditional significance, phytochemistry, and pharmacology

MM Rahman, S Bibi, MS Rahaman, F Rahman… - Biomedicine & …, 2022 - Elsevier
Background Lung diseases including chronic obstructive pulmonary disease (COPD),
infections like influenza, acute respiratory distress syndrome (ARDS), asthma and …

[HTML][HTML] Wnt/β-catenin signaling in liver cancers

W Wang, R Smits, H Hao, C He - Cancers, 2019 - mdpi.com
Liver cancer is among the leading global healthcare issues associated with high morbidity
and mortality. Liver cancer consists of hepatocellular carcinoma (HCC), cholangiocarcinoma …

Targeting the Wnt pathway in human cancers: therapeutic targeting with a focus on OMP-54F28

PN Le, JD McDermott, A Jimeno - Pharmacology & therapeutics, 2015 - Elsevier
The Wnt signaling pathways are a group of signal transduction pathways that play an
important role in cell fate specification, cell proliferation and cell migration. Aberrant …

Von Hippel-Lindau disease: current challenges and future prospects

S Gläsker, E Vergauwen, CA Koch… - OncoTargets and …, 2020 - Taylor & Francis
Understanding of molecular mechanisms of tumor growth has an increasing impact on the
development of diagnostics and targeted therapy of human neoplasia. In this review, we …

Salinomycin as a potent anticancer stem cell agent: State of the art and future directions

D Qi, Y Liu, J Li, JH Huang, X Hu… - Medicinal research …, 2022 - Wiley Online Library
Cancer stem cells (CSCs) are a small subpopulation of cells within a tumor that can both self‐
renew and differentiate into other cell types forming the heterogeneous tumor bulk. Since …

Salinomycin: A new paradigm in cancer therapy

J Dewangan, S Srivastava, SK Rath - Tumor Biology, 2017 - journals.sagepub.com
The primary hurdle in the treatment of cancer is acquisition of resistance by the tumor cells
toward multiple drugs and selectively targeting the cancer stem cells. This problem was …

Lung cancer stem cells and cancer stem cell-targeting natural compounds

A Maiuthed, W Chantarawong… - Anticancer …, 2018 - ar.iiarjournals.org
The novel information regarding molecular and translational research have created a
paradigm shift in the understanding of lung cancer biology, revealing the more precise target …

Combination of salinomycin and silver nanoparticles enhances apoptosis and autophagy in human ovarian cancer cells: an effective anticancer therapy

XF Zhang, S Gurunathan - International journal of nanomedicine, 2016 - Taylor & Francis
Ovarian cancer is one of the most important malignancies, and the origin, detection, and
pathogenesis of epithelial ovarian cancer remain elusive. Although many cancer drugs have …

Salinomycin inhibits breast cancer progression via targeting HIF-1α/VEGF mediated tumor angiogenesis in vitro and in vivo

J Dewangan, S Srivastava, S Mishra, A Divakar… - Biochemical …, 2019 - Elsevier
Cancer is a complex disease wherein cells begin to divide abnormally and spread into
surrounding tissues. Angiogenesis plays a crucial role in tumor progression as it is required …

[HTML][HTML] Salinomycin suppresses TGF-β1-induced EMT by down-regulating MMP-2 and MMP-9 via the AMPK/SIRT1 pathway in non-small cell lung cancer

KE Hwang, HJ Kim, IS Song, C Park… - … journal of medical …, 2021 - ncbi.nlm.nih.gov
Salinomycin (Sal) is a recently identified anti-tumor drug for treating several types of solid
tumor; however, its effects on the migratory and invasive properties of non-small cell lung …