Early electron microscopy studies revealed the elaborate cellular features that define the
unique adaptations of apicomplexan parasites. Among these were bulbous rhoptry (ROP) …

Oxygen is essential for eukaryotic life and is inextricably linked to the evolution of
multicellular organisms. Proper cellular response to changes in oxygen tension during …

Toxoplasmosis is the clinical and pathological consequence of acute infection with the
obligate intracellular apicomplexan parasite Toxoplasma gondii. Symptoms result from …

The function of metabolic state in stemness is poorly understood. Mouse embryonicstem
cells (ESC) and epiblast stem cells (EpiSC) are at distinct pluripotent statesrepresenting the …

Toxoplasma gondii is an intracellular protozoan parasite of global importance that can
remarkably infect, survive, and replicate in nearly all mammalian cells. Notably, 110 years …

During infections with the protozoan parasite Toxoplasma gondii, gamma-aminobutyric acid
(GABA) is utilized as a carbon source for parasite metabolism and also to facilitate parasite …

For most of the living beings, oxygen is one of the essential elements required to sustain life.
Deprivation of oxygen causes tissue hypoxia and this severely affects host cell and organ …

The epigenetics of host–pathogen interactions is emerging as an interesting angle from
which to study how parasites have evolved sophisticated strategies to manipulate host gene …

HLA class I presentation of pathogen-derived peptide ligands is essential for CD8+ T-cell
recognition of Toxoplasma gondii infected cells. Currently, little data exist pertaining to …

Toxoplasma gondii severely threaten the health of immunocompromised patients and
pregnant women as this parasite can cause several disease, including brain and eye …