Therapeutic Potential of Centella asiatica and Its Triterpenes: A Review

B Sun, L Wu, Y Wu, C Zhang, L Qin… - Frontiers in …, 2020 - frontiersin.org
Centella asiatica (also known as Centella asiatica (L.) Urb. or Gotu kola) is a traditional
Chinese medicine with extensive medicinal value, which is commonly used in Southeast …

Regulated cell death: discovery, features and implications for neurodegenerative diseases

J Cui, S Zhao, Y Li, D Zhang, B Wang, J Xie… - Cell Communication and …, 2021 - Springer
Regulated cell death (RCD) is a ubiquitous process in living organisms that is essential for
tissue homeostasis or to restore biological balance under stress. Over the decades, various …

Pharmacological properties, molecular mechanisms, and pharmaceutical development of asiatic acid: a pentacyclic triterpenoid of therapeutic promise

MF Nagoor Meeran, SN Goyal, K Suchal… - Frontiers in …, 2018 - frontiersin.org
Asiatic acid (AA) is a naturally occurring aglycone of ursane type pentacyclic triterpenoids. It
is abundantly present in many edible and medicinal plants including Centella asiatica that is …

Neuroprotective potentials of Lead phytochemicals against Alzheimer's disease with focus on oxidative stress-mediated signaling pathways: Pharmacokinetic …

M Ayaz, OF Mosa, A Nawaz, AAE Hamdoon… - Phytomedicine, 2024 - Elsevier
Background Alzheimer's diseases (AD) and dementia are among the highly prevalent
neurological disorders characterized by deposition of beta amyloid (Aβ) plaques, dense …

Actions and Therapeutic Potential of Madecassoside and Other Major Constituents of Centella asiatica: A Review

SC Tan, SK Bhattamisra, DK Chellappan… - Applied Sciences, 2021 - mdpi.com
Centella asiatica is a popular herb well-known for its wide range of therapeutic effects and
its use as a folk medicine for many years. Its therapeutic properties have been well …

Asiatic acid attenuated aluminum chloride-induced tau pathology, oxidative stress and apoptosis via AKT/GSK-3β signaling pathway in wistar rats

M Ahmad Rather, A Justin-Thenmozhi… - Neurotoxicity …, 2019 - Springer
Asiatic acid (AA), a triterpenoid present in Centella asiatica, possesses the ability to cross
blood brain barrier and received considerable attention for its neuroprotective role. We have …

Traditional herbal medicines against CNS disorders from Bangladesh

MJ Uddin, C Zidorn - Natural Products and Bioprospecting, 2020 - Springer
The majority of the population in Bangladesh uses traditional plant-based medicines to
manage various ailments, including central nervous system (CNS) disorders. This review …

Treatment of Alzheimer's disease with framework nucleic acids

X Shao, W Cui, X Xie, W Ma, Y Zhan, Y Lin - Cell Proliferation, 2020 - Wiley Online Library
Objectives To provide a new research direction for nerve regeneration and strategy for
Alzheimer's disease treatment, tetrahedral DNA nanostructures (TDNs)—novel tetrahedral …

Neuroprotective effect of nose-to-brain delivery of Asiatic acid in solid lipid nanoparticles and its mechanisms against memory dysfunction induced by Amyloid Beta1 …

R Islamie, SLL Myint, T Rojanaratha, G Ritthidej… - … Medicine and Therapies, 2023 - Springer
Abstract Background Amyloid-β1-42 (Aβ1-42) plays an essential role in the development of
the early stage of Alzheimer's disease (AD). Asiatic acid (AA), an active compound in …

Selective sacrificial metal–organic frameworks: a highly quantitative colorimetric naked-eye detector for aluminum ions in aqueous solutions

F Rouhani, F Rafizadeh-Masuleh… - Journal of Materials …, 2019 - pubs.rsc.org
The detection, differentiation, and especially visual quantification of target compounds are
important and interesting challenges for researchers. The quantitative diagnosis of …