Progress in biological cancer characterization, targeted systemic therapies and
multimodality treatment strategies have shifted the goals of radiotherapy for spinal …

The oligometastatic state is hypothesized to represent an intermediary state of cancer
between widely metastatic disease and curable, localized disease. Advancements in …

Malignant spinal cord compression (MSCC) is one of the most devastating complications of
cancer. Patients often present with a history of progressive pain, paralysis, sensory loss …

Spine metastases affect more than 70% of terminal cancer patients that eventually suffer
from severe pain and neurological symptoms. Nevertheless, in the overwhelming majority of …

Complications in spine surgery can arise in the intraoperative or the immediate
postoperative period or in a delayed manner. These complications may lead to severe or …

Purpose Renal cell carcinoma is refractory to conventional radiation therapy but responds to
higher doses per fraction. However, the dosimetric data and clinical factors affecting local …

Purpose We sought to investigate the tumor control probability (TCP) of spinal metastases
treated with stereotactic body radiation therapy (SBRT) in 1 to 5 fractions. Methods and …

Background: Stereotactic body radiotherapy (SBRT) is an emerging treatment option for
spinal metastases with demonstrated efficacy in the upfront, postoperative, and re-treatment …

Patients with metastatic disease including polymetastatic, oligometastatic, and
oligorecurrent spinal lesions have extended life expectancy secondary to improvements in …

Stereotactic body radiation therapy and stereotactic radiosurgery have become important
treatment options for the treatment of spinal malignancies. A better understanding of dose …