Immunogenomics parameters for patient stratification in Alzheimer's disease
Background: Despite the fact that only modest adaptive immune system related approaches
to treating Alzheimer's disease (AD) are available, an immunogenomics approach to the …
to treating Alzheimer's disease (AD) are available, an immunogenomics approach to the …
Specific TCR V–J gene segment recombinations leading to the identification pan-V–J CDR3s associated with survival distinctions: diffuse large B-cell lymphoma
KJ Cios, TI Huda, RA Eakins, MM Mihyu… - Leukemia & …, 2022 - Taylor & Francis
In the diffuse large B-cell lymphoma (DLBCL) setting, we examined lymph node biopsy, T-
cell receptor features, and the DLBLC patient human leukocyte antigen (HLA) alleles, to …
cell receptor features, and the DLBLC patient human leukocyte antigen (HLA) alleles, to …
Exploiting big data survival information to unify risk-stratification related, adaptive immune receptor parameters for multiple myeloma
HJ Wolmarans, VR Barker, A Chobrutskiy… - Genes & …, 2023 - nature.com
With the improvement of treatment options, multiple myeloma related life expectancy has
been prolonged, but the disease remains largely incurable. Immunotherapy is a growing …
been prolonged, but the disease remains largely incurable. Immunotherapy is a growing …
TRB CDR3-cancer testis antigen chemical complementarity scoring for identifying productive immune responses in renal cell carcinoma
TR Hudock, VR Barker, BJ Manley… - Cancer …, 2023 - content.iospress.com
BACKGROUND: Immunogenomics approaches to the characterization of renal cell
carcinoma (RCC) have helped to better our understanding of the features of RCC immune …
carcinoma (RCC) have helped to better our understanding of the features of RCC immune …
TCR gene segment usage and HLA alleles that are associated with cancer survival rates also represent racial disparities
G Angelakakis, KS Serraneau… - International Journal …, 2023 - Wiley Online Library
Understanding racial disparities in cancer outcomes continues to be a challenge, with likely
many factors at play, including socioeconomic factors and genetic polymorphisms impacting …
many factors at play, including socioeconomic factors and genetic polymorphisms impacting …
Immune receptor CDR3 chemical features that preserve sequence information are highly efficient in reflecting survival distinctions: A pan‑cancer analysis
BE Mcbreairty, BI Chobrutskiy… - Biomedical …, 2022 - spandidos-publications.com
Adaptive immune receptor (IR) chemical features have been used as signatures of an
immune response for numerous medical conditions, raising the question of whether certain …
immune response for numerous medical conditions, raising the question of whether certain …