Thymoquinone and its therapeutic potentials

S Darakhshan, AB Pour, AH Colagar… - Pharmacological …, 2015 - Elsevier
Herbal medicine has attracted great attention in the recent years and is increasingly used as
alternatives to chemical drugs. Several lines of evidence support the positive impact of …

Preclinical and clinical effects of Nigella sativa and its constituent, thymoquinone: A review

Z Gholamnezhad, S Havakhah… - Journal of …, 2016 - Elsevier
Ethnopharmacological relevance Nigella sativa (N. sativa) L.(Ranunculaceae), well known
as black cumin, has been used as a herbal medicine that has a rich historical background. It …

Potential influence of Nagella sativa (Black cumin) in reinforcing immune system: A hope to decelerate the COVID-19 pandemic

MFA Kulyar, R Li, K Mehmood, M Waqas, K Li, J Li - Phytomedicine, 2021 - Elsevier
The world is witnessing a difficult time. The race of developing a new coronavirus (COVID-
19) vaccine is becoming more urgent. Many preliminary studies on the pathophysiology of …

Phytochemical characterization and antimicrobial activity of Nigella sativa seeds

FS Shafodino, JM Lusilao, LM Mwapagha - PloS one, 2022 - journals.plos.org
Nigella sativa is one of the medicinal plant species that gained popularity for a wide range of
medicinal applications due to its seeds which are rich in phytoconstituents. Continuous …

Thymoquinone extracted from black seed triggers apoptotic cell death in human colorectal cancer cells via a p53-dependent mechanism

H Gali-Muhtasib, M Diab-Assaf… - International …, 2004 - spandidos-publications.com
For centuries, the black seed (Nigella sativa) herb and oil have been used in Asia, Middle
East and Africa to promote health and fight disease. Thymoquinone (TQ), the most abundant …

A narrative review on various oil extraction methods, encapsulation processes, fatty acid profiles, oxidative stability, and medicinal properties of black seed (Nigella …

MA Rahim, A Shoukat, W Khalid, A Ejaz, N Itrat… - Foods, 2022 - mdpi.com
The current review investigates the effects of black seed (Nigella sativa) on human health,
which is also used to encapsulate and oxidative stable in different food products. In recent …

Thymoquinone induces apoptosis through activation of caspase‐8 and mitochondrial events in p53‐null myeloblastic leukemia HL‐60 cells

MA El‐Mahdy, Q Zhu, QE Wang… - … journal of cancer, 2005 - Wiley Online Library
Thymoquinone (TQ), the major biologically active component isolated from a traditional
medicinal herb, Nigella sativa Linn, is a potential chemopreventive and chemotherapeutic …

[HTML][HTML] Anticancer activity of thymoquinone against breast cancer cells: Mechanisms of action and delivery approaches

H Shabani, MH Karami, J Kolour, Z Sayyahi… - Biomedicine & …, 2023 - Elsevier
The rising incidence of breast cancer has been a significant source of concern in the
medical community. Regarding the adverse effects and consequences of current treatments …

The neuroprotective effects of thymoquinone: a review

T Farkhondeh, S Samarghandian… - Dose …, 2018 - journals.sagepub.com
Thymoquinone (TQ), one of the main components active of Nigella sativa, exhibited very
useful biomedical effects such as anti-inflammatory, antioxidant, antimicrobial, antiparasitic …

[HTML][HTML] The effects of thymoquinone on pancreatic cancer: Evidence from preclinical studies

M Butnariu, C Quispe, J Herrera-Bravo, P Helon… - Biomedicine & …, 2022 - Elsevier
Thymoquinone (TQ) is a secondary metabolite found in abundance in very few plant species
including Nigella sativa L., Monarda fistulosa L., Thymus vulgaris L. and Satureja montana …