Kerri B. Gosselin, MD, MPH, and Christopher Duggan, MD, MPH Intestinal failure (IF) is an
uncommon but devastating condition whose natural history has dramatically improved over …

Tumor invasion along structural interphases of surrounding tumor-free tissue represents a
key process during tumor progression. Much attention has been devoted to mechanisms of …

Multiple culture techniques now exist for the long-term maintenance of neonatal primary
murine intestinal organoids in vitro; however, the achievement of contractile behavior within …

Though in vitro culture of primary intestinal organoids has gained significant momentum in
recent years, little has been done to investigate the impact of microenvironmental cues …

In recent years, three-dimensional (3D) cell culture models of the small intestine have
gained much attention. These models support cell proliferation, migration, and differentiation …

If one were to compare today's animal growth research to research from a mere 50 yr ago,
one would see programs with few similarities. The evolution of this research from whole …

Although critical for studies of gut motility and intestinal regeneration, the in vitro culture of
intestinal muscularis with peristaltic function remains a significant challenge. Periodic …

Highlights•Scaffolds in tissue engineering are used as temporary matrix for the cells.•In vitro
and in vivo studies were conducted to test cell–biomaterial interaction.•The proposed …

The intestinal muscle layers execute various gut wall movements to achieve controlled
propulsion and mixing of intestinal content. Engineering intestinal muscle layers with …

Stem cell research and the use of stem cells in therapy have seen tremendous growth in the
last two decades. Neonatal intestinal disorders such as necrotizing enterocolitis …