This review describes the definition, incidence, clinical implications, and magnetic
resonance imaging (MRI) findings of pseudoprogression of brain tumors, in particular, but …

Localized proton magnetic resonance spectroscopy (MRS) of the human brain, first reported
more than 20 years ago, 1–3 is a mature methodology that is used clinically in many medical …

It remains difficult to distinguish tumor recurrence from radiation necrosis after brain tumor
therapy. Here we show that these lesions can be distinguished using the amide proton …

Imaging techniques are important for accurate diagnosis and follow-up of patients with
gliomas. T1-weighted MRI, with or without gadolinium, is the gold standard method …

Abstract Purpose of Review This review will explore the latest in advanced imaging
techniques, with a focus on the complementary nature of multiparametric, multimodality …

Purpose To investigate whether cerebral blood volume (CBV), peak height (PH), and
percentage of signal intensity recovery (PSR) measurements derived from the results of T2 …

Eighty percent of all malignant primary brain tumors diagnosed in the United States are
gliomas. 1 The current treatment paradigm for high-grade gliomas (grades III and IV) …

BACKGROUND AND PURPOSE: Differentiating tumor growth from posttreatment radiation
effect (PTRE) remains a common problem in neuro-oncology practice. To our knowledge …

Differentiating treatment-induced necrosis from tumor recurrence is a central challenge in
neuro-oncology. These 2 very different outcomes after brain tumor treatment often appear …

We evaluated the diagnostic accuracy of PET with l-methyl-11C-methionine (11C-MET) for
the differentiation of recurrent brain tumors from radiation necrosis. Methods: Seventy-seven …