Sex hormone signaling and regulation of immune function
Immune responses to antigens, including innocuous, self, tumor, microbial, and vaccine
antigens, differ between males and females. The quest to uncover the mechanisms for …
antigens, differ between males and females. The quest to uncover the mechanisms for …
Connecting the mechanisms of tumor sex differences with cancer therapy
H Li, W Jiang, S Liu, M Yang, S Chen, Y Pan… - Molecular and Cellular …, 2024 - Springer
Sex differences in cancer incidence and survival are constant and pronounced globally,
across all races and all age groups of cancer types. In 2016, after the National Institutes of …
across all races and all age groups of cancer types. In 2016, after the National Institutes of …
[HTML][HTML] Elevated FBXW10 drives hepatocellular carcinoma tumorigenesis via AR-VRK2 phosphorylation-dependent GAPDH ubiquitination in male transgenic mice
XT Lin, J Zhang, ZY Liu, D Wu, L Fang, CM Li, HQ Yu… - Cell Reports, 2023 - cell.com
Hepatocellular carcinoma (HCC), the most common liver cancer, occurs mainly in men, but
the underlying mechanism remains to be further explored. Here, we report that ubiquitinated …
the underlying mechanism remains to be further explored. Here, we report that ubiquitinated …
[HTML][HTML] Single-cell profiling of murine bladder cancer identifies sex-specific transcriptional signatures with prognostic relevance
HA Abdel-Hafiz, SKK Mani, W Huang, KH Gouin… - Iscience, 2023 - cell.com
Bladder cancer (BLCA) is more common in men but more aggressive in women. Sex-based
differences in cancer biology are commonly studied using a murine model with BLCA …
differences in cancer biology are commonly studied using a murine model with BLCA …
Landscape of exhausted T cells in tuberculosis revealed by single-cell sequencing
J Pan, X Zhang, J Xu, Z Chang, Z Xin… - Microbiology …, 2023 - Am Soc Microbiol
Tuberculosis, a contagious bacterial infection caused by Mycobacterium tuberculosis, is a
substantial global health problem, impacting millions of lives annually. Exhausted T-cell …
substantial global health problem, impacting millions of lives annually. Exhausted T-cell …
Androgens in cervical cancer: Their role in epidemiology and biology
Y Gu, Q Mu, D Cheng - Iscience, 2024 - cell.com
This comprehensive review delves into the significance of androgens in cervical cancer,
examining both epidemiological evidence and the underlying biological mechanisms …
examining both epidemiological evidence and the underlying biological mechanisms …
[HTML][HTML] Progestogen-driven B7-H4 contributes to onco-fetal immune tolerance
Immune tolerance mechanisms are shared in cancer and pregnancy. Through cross-
analyzing single-cell RNA-sequencing data from multiple human cancer types and the …
analyzing single-cell RNA-sequencing data from multiple human cancer types and the …
[引用][C] Single-cell profiling of murine bladder cancer identifies sex-specific transcriptional signatures with prognostic relevance
S Hafiz, K Kailasam, W Mani, SRV Knott… - europepmc.org
Bladder cancer (BLCA) is more common in men but more aggressive in women. Sex-based
differences in cancer biology are commonly studied using a murine model with BLCA …
differences in cancer biology are commonly studied using a murine model with BLCA …