There is convincing evidence that environmental stress plays a significant role in modifying
both mental and physical health. The biological mechanisms linking stress to ill health are …

Up to now studies on hypothalamic–pituitary–adrenal (HPA) axis activity in psychosis have
shown inconsistent findings. These inconsistencies have been often ascribed to …

Introduction Antipsychotics (AP) induce weight gain. However, reviews and meta-analyses
generally are restricted to second generation antipsychotics (SGA) and do not stratify for …

Increased peripheral levels of morning cortisol have been reported in people with
schizophrenia (SZ) and bipolar disorder (BD), but findings are inconsistent and few studies …

First-episode psychosis (FEP) patients show hyperactivity of the hypothalamic–pituitary–
adrenal (HPA) axis, but the mechanisms leading to this are still unclear. The aim of this study …

Prescriptions for second-generation antipsychotics (SGAs) have surpassed those for first-
generation agents in the treatment of schizophrenia and bipolar disorder. While SGAs have …

First seen as a fat-storage tissue, the adipose tissue is considered as a critical player in the
endocrine system. Precisely, adipose tissue can produce an array of bioactive factors …

Beside the therapeutic improvement over first-generation antipsychotics, the fact that
prescription of atypical agents is also associated to the emergence of severe metabolic …

OBJECTIVE: To explore the impact of premorbid and baseline body mass indices (BMIs) as
well as BMI of patient's parents and associated variables on the prediction of antipsychotic …

The prevalence of overweight and obesity is higher in people with mental illness than in the
general population. Body weight is tightly regulated by a complex system involving the …