The cannabis derivative marijuana is the most widely used recreational drug in the Western
world and is consumed by an estimated 83 million individuals (∼ 3% of the world …

Myrcene (β-myrcene) is an abundant monoterpene which occurs as a major constituent in
many plant species, including hops and cannabis. It is a popular flavouring and aroma agent …

Cannabis has been used for medicinal purposes for thousands of years. The prohibition of
cannabis in the middle of the 20th century has arrested cannabis research. In recent years …

Epidemiological studies reveal that marijuana increases the risk of cardiovascular disease
(CVD); however, little is known about the mechanism. Δ 9-tetrahydrocannabinol (Δ 9-THC) …

Drugs selectively targeting CB2 hold promise for treating neurodegenerative disorders,
inflammation, and pain while avoiding psychotropic side effects mediated by CB1. The …

Microglia are key to maintaining the homeostasis of the brain. These immune cells of the
brain can be our biggest ally in fighting infections, but can worsen pathology or hinder …

The endocannabinoid system (ECS) has lately been proven to be an important, multifaceted
homeostatic regulator, which influences a wide-variety of physiological processes all over …

The liver microcirculatory milieu, mainly composed of liver sinusoidal endothelial cells
(LSECs), hepatic stellate cells (HSCs) and hepatic macrophages, has an essential role in …

The type 2 cannabinoid receptor (CB2R) was initially regarded as a peripheral cannabinoid
receptor. However, recent technological advances in gene detection, alongside the …

The endocannabinoid system (ECS) is one of the most crucial systems in the human
organism, exhibiting multi-purpose regulatory character. It is engaged in a vast array of …