OBJECTIVE: Description of the various autoantibodies that can be detected in patients with
systemic lupus erythematosus (SLE). METHODS: A literature review, using the terms …

Scleroderma (systemic sclerosis) is associated with several autoantibodies, each of which is
useful in the diagnosis of affected patients and in determining their prognosis. Anti …

Distinct profiles of autoantibodies directed to intracellular antigens can be detected in the
systemic connective tissue diseases. They aid in establishing the correct diagnosis and are …

The autoantibodies classically associated with systemic sclerosis (SSc; scleroderma)
include anticentromere antibodies (ACA) and anti–Scl-70 (otherwise known as anti …

Signaling thresholds influence the balance between humoral immunity and autoimmunity.
Cell surface CD19 regulates intrinsic and Ag receptor-induced B lymphocyte signaling …

Objective: To determine the clinical significance of anti-RNA polymerase III antibody in
systemic sclerosis (SSc). Design: A point prevalence study of autoantibody to RNA …

The observation that revelation of immunocryptic epitopes in self antigens may initiate the
autoimmune response has prompted the search for processes which induce novel …

Sera from 735 patients with systemic sclerosis were classified according to antinuclear
antibody (ANA) pattern as follows: centromere (25%), homogeneous (26%), fine speckled …

Nutrient-driven O-GlcNAcylation of key components of the transcription machinery may
epigenetically modulate gene expression in metazoans. The global effects of GlcNAcylation …

The presence of antinuclear antibodies (ANAs) is a central feature of systemic sclerosis
(SSc) or scleroderma. 77,120 Although the mechanisms of ANA production are incompletely …