Phylogeny of the SOX family of developmental transcription factors based on sequence and structural indicators

J Bowles, G Schepers, P Koopman - Developmental biology, 2000 - Elsevier
Members of the SOX family of transcription factors are found throughout the animal kingdom,
are characterized by the presence of a DNA-binding HMG domain, and are involved in a …

From head to toes: the multiple facets of Sox proteins

M Wegner - Nucleic acids research, 1999 - academic.oup.com
Sox proteins belong to the HMG box superfamily of DNA-binding proteins and are found
throughout the animal kingdom. They are involved in the regulation of such diverse …

Sry: the master switch in mammalian sex determination

K Kashimada, P Koopman - Development, 2010 - journals.biologists.com
SRY, the mammalian Y-chromosomal testis-determining gene, induces male sex
determination. Recent studies in mice reveal that the major role of SRY is to achieve …

[HTML][HTML] Sex determination and gonadal development in mammals

D Wilhelm, S Palmer, P Koopman - Physiological reviews, 2007 - journals.physiology.org
Arguably the most defining moment in our lives is fertilization, the point at which we inherit
either an X or a Y chromosome from our father. The profoundly different journeys of male …

Direct interaction of SRY-related protein SOX9 and steroidogenic factor 1 regulates transcription of the human anti-Mullerian hormone gene

P De Santa Barbara, N Bonneaud… - … and cellular biology, 1998 - Am Soc Microbiol
For proper male sexual differentiation, anti-Müllerian hormone (AMH) must be tightly
regulated during embryonic development to promote regression of the Müllerian duct …

Physiological substrates of cAMP-dependent protein kinase

JB Shabb - Chemical reviews, 2001 - ACS Publications
The purpose of this review is to provide an account of the physiological substrates of cAMP-
dependent protein kinase (PKA). Discussion is limited to just over 100 unique gene products …

[图书][B] Making sex revisited: Dekonstruktion des Geschlechts aus biologisch-medizinischer Perspektive

HJ Voß - 2015 - library.oapen.org
Die fortgesetzte Suche nach dem einzelnen ‚geschlechtsdeterminierenden Gen ': SRY als
TDF? 250 Downstream von SRY–weitere Gene, die hierarchisch unterhalb von SRY als an …

SOX family transcription factors involved in diverse cellular events during development

ZY She, WX Yang - European journal of cell biology, 2015 - Elsevier
In metazoa, SOX family transcription factors play many diverse roles. In vertebrate, they are
well-known regulators of numerous developmental processes. Wide-ranging studies have …

Origin, differentiation and regulation of fetal and adult Leydig cells

R Habert, H Lejeune, JM Saez - Molecular and cellular endocrinology, 2001 - Elsevier
Mammalian sex determination involves complex interacting networks of cellular and
hormonal signals leading to the development of male or female phenotype. Three main …

Phosphorylation of SOX9 by cyclic AMP-dependent protein kinase a enhances SOX9's ability to transactivate aCol2a1 chondrocyte-specific enhancer

W Huang, X Zhou, V Lefebvre… - Molecular and cellular …, 2000 - Am Soc Microbiol
Sox9 is a high-mobility-group domain-containing transcription factor required for
chondrocyte differentiation and cartilage formation. We used a yeast two-hybrid method …