Phylogeny of the SOX family of developmental transcription factors based on sequence and structural indicators
Members of the SOX family of transcription factors are found throughout the animal kingdom,
are characterized by the presence of a DNA-binding HMG domain, and are involved in a …
are characterized by the presence of a DNA-binding HMG domain, and are involved in a …
From head to toes: the multiple facets of Sox proteins
M Wegner - Nucleic acids research, 1999 - academic.oup.com
Sox proteins belong to the HMG box superfamily of DNA-binding proteins and are found
throughout the animal kingdom. They are involved in the regulation of such diverse …
throughout the animal kingdom. They are involved in the regulation of such diverse …
Sry: the master switch in mammalian sex determination
K Kashimada, P Koopman - Development, 2010 - journals.biologists.com
SRY, the mammalian Y-chromosomal testis-determining gene, induces male sex
determination. Recent studies in mice reveal that the major role of SRY is to achieve …
determination. Recent studies in mice reveal that the major role of SRY is to achieve …
[HTML][HTML] Sex determination and gonadal development in mammals
Arguably the most defining moment in our lives is fertilization, the point at which we inherit
either an X or a Y chromosome from our father. The profoundly different journeys of male …
either an X or a Y chromosome from our father. The profoundly different journeys of male …
Direct interaction of SRY-related protein SOX9 and steroidogenic factor 1 regulates transcription of the human anti-Mullerian hormone gene
P De Santa Barbara, N Bonneaud… - … and cellular biology, 1998 - Am Soc Microbiol
For proper male sexual differentiation, anti-Müllerian hormone (AMH) must be tightly
regulated during embryonic development to promote regression of the Müllerian duct …
regulated during embryonic development to promote regression of the Müllerian duct …
Physiological substrates of cAMP-dependent protein kinase
JB Shabb - Chemical reviews, 2001 - ACS Publications
The purpose of this review is to provide an account of the physiological substrates of cAMP-
dependent protein kinase (PKA). Discussion is limited to just over 100 unique gene products …
dependent protein kinase (PKA). Discussion is limited to just over 100 unique gene products …
[图书][B] Making sex revisited: Dekonstruktion des Geschlechts aus biologisch-medizinischer Perspektive
HJ Voß - 2015 - library.oapen.org
Die fortgesetzte Suche nach dem einzelnen ‚geschlechtsdeterminierenden Gen ': SRY als
TDF? 250 Downstream von SRY–weitere Gene, die hierarchisch unterhalb von SRY als an …
TDF? 250 Downstream von SRY–weitere Gene, die hierarchisch unterhalb von SRY als an …
SOX family transcription factors involved in diverse cellular events during development
ZY She, WX Yang - European journal of cell biology, 2015 - Elsevier
In metazoa, SOX family transcription factors play many diverse roles. In vertebrate, they are
well-known regulators of numerous developmental processes. Wide-ranging studies have …
well-known regulators of numerous developmental processes. Wide-ranging studies have …
Origin, differentiation and regulation of fetal and adult Leydig cells
R Habert, H Lejeune, JM Saez - Molecular and cellular endocrinology, 2001 - Elsevier
Mammalian sex determination involves complex interacting networks of cellular and
hormonal signals leading to the development of male or female phenotype. Three main …
hormonal signals leading to the development of male or female phenotype. Three main …
Phosphorylation of SOX9 by cyclic AMP-dependent protein kinase a enhances SOX9's ability to transactivate aCol2a1 chondrocyte-specific enhancer
W Huang, X Zhou, V Lefebvre… - Molecular and cellular …, 2000 - Am Soc Microbiol
Sox9 is a high-mobility-group domain-containing transcription factor required for
chondrocyte differentiation and cartilage formation. We used a yeast two-hybrid method …
chondrocyte differentiation and cartilage formation. We used a yeast two-hybrid method …