A review of liposomes as a drug delivery system: current status of approved products, regulatory environments, and future perspectives
P Liu, G Chen, J Zhang - Molecules, 2022 - mdpi.com
Liposomes have been considered promising and versatile drug vesicles. Compared with
traditional drug delivery systems, liposomes exhibit better properties, including site …
traditional drug delivery systems, liposomes exhibit better properties, including site …
The enhanced permeability and retention (EPR) effect: the significance of the concept and methods to enhance its application
J Wu - Journal of personalized medicine, 2021 - mdpi.com
Chemotherapy for human solid tumors in clinical practice is far from satisfactory. Despite the
discovery and synthesis of hundreds of thousands of anticancer compounds targeting …
discovery and synthesis of hundreds of thousands of anticancer compounds targeting …
The exit of nanoparticles from solid tumours
Nanoparticles enter tumours through endothelial cells, gaps or other mechanisms, but how
they exit is unclear. The current paradigm states that collapsed tumour lymphatic vessels …
they exit is unclear. The current paradigm states that collapsed tumour lymphatic vessels …
Bioorthogonal chemistry and its applications
RE Bird, SA Lemmel, X Yu, QA Zhou - Bioconjugate Chemistry, 2021 - ACS Publications
Bioorthogonal chemistry is a set of methods using the chemistry of non-native functional
groups to explore and understand biology in living organisms. In this review, we summarize …
groups to explore and understand biology in living organisms. In this review, we summarize …
Nanoparticle-based drug delivery in cancer therapy and its role in overcoming drug resistance
Y Yao, Y Zhou, L Liu, Y Xu, Q Chen, Y Wang… - Frontiers in molecular …, 2020 - frontiersin.org
Nanotechnology has been extensively studied and exploited for cancer treatment as
nanoparticles can play a significant role as a drug delivery system. Compared to …
nanoparticles can play a significant role as a drug delivery system. Compared to …
Emerging applications of nanotechnology in healthcare and medicine
S Malik, K Muhammad, Y Waheed - Molecules, 2023 - mdpi.com
Knowing the beneficial aspects of nanomedicine, scientists are trying to harness the
applications of nanotechnology in diagnosis, treatment, and prevention of diseases. There …
applications of nanotechnology in diagnosis, treatment, and prevention of diseases. There …
[HTML][HTML] Multidisciplinary strategies to enhance therapeutic effects of flavonoids from Epimedii Folium: Integration of herbal medicine, enzyme engineering, and …
Flavonoids such as baohuoside I and icaritin are the major active compounds in Epimedii
Folium (EF) and possess excellent therapeutic effects on various diseases. Encouragingly …
Folium (EF) and possess excellent therapeutic effects on various diseases. Encouragingly …
Strategies to enhance drug delivery to solid tumors by harnessing the EPR effects and alternative targeting mechanisms
Abstract The Enhanced Permeability and Retention (EPR) effect has been recognized as the
central paradigm in tumor-targeted delivery in the last decades. In the wake of this concept …
central paradigm in tumor-targeted delivery in the last decades. In the wake of this concept …
[HTML][HTML] Cellular uptake and retention of nanoparticles: Insights on particle properties and interaction with cellular components
The utilization of nanomaterials in the biological and medical field is quickly progressing,
particularly in areas where traditional diagnostics and treatment approaches have limited …
particularly in areas where traditional diagnostics and treatment approaches have limited …
Tumor-targeted cascade nanoreactor based on metal–organic frameworks for synergistic ferroptosis–starvation anticancer therapy
X Wan, L Song, W Pan, H Zhong, N Li, B Tang - ACS nano, 2020 - ACS Publications
Although ferroptosis therapy has been proven to be a promising strategy for cancer
treatment, its efficacy still might be limited by insufficient H2O2 supply in tumor tissue …
treatment, its efficacy still might be limited by insufficient H2O2 supply in tumor tissue …