What is lipotoxicity?
AB Engin - Obesity and lipotoxicity, 2017 - Springer
Enlarged fat cells in obese adipose tissue diminish capacity to store fat and are resistant to
the anti-lipolytic effect of insulin. Insulin resistance (IR)-associated S-nitrosylation of insulin …
the anti-lipolytic effect of insulin. Insulin resistance (IR)-associated S-nitrosylation of insulin …
White adipose tissue mitochondrial metabolism in health and in obesity
S Heinonen, R Jokinen, A Rissanen… - Obesity …, 2020 - Wiley Online Library
White adipose tissue is one of the largest organs of the body. It plays a key role in whole‐
body energy status and metabolism; it not only stores excess energy but also secretes …
body energy status and metabolism; it not only stores excess energy but also secretes …
The regulatory role of adipocyte mitochondrial homeostasis in metabolism-related diseases
H Song, X Zhang, J Wang, Y Wu, T Xiong… - Frontiers in …, 2023 - frontiersin.org
Adipose tissue is the most important energy storage organ in the body, maintaining its
normal energy metabolism function and playing a vital role in keeping the energy balance of …
normal energy metabolism function and playing a vital role in keeping the energy balance of …
[HTML][HTML] Expression of lipid metabolism genes provides new insights into intramuscular fat deposition in Laiwu pigs
H Wang, J Wang, D Yang, Z Liu, Y Zeng… - … -Australasian journal of …, 2020 - ncbi.nlm.nih.gov
Objective The objective of this study was to measure the special expression pattern of lipid
metabolism genes and investigate the molecular mechanisms underlying intramuscular fat …
metabolism genes and investigate the molecular mechanisms underlying intramuscular fat …
Trapped fat: Obesity pathogenesis as an intrinsic disorder in metabolic fuel partitioning
MI Friedman, TIA Sørensen, G Taubes, J Lund… - Obesity …, 2024 - Wiley Online Library
Our understanding of the pathophysiology of obesity remains at best incomplete despite a
century of research. During this time, two alternative perspectives have helped shape …
century of research. During this time, two alternative perspectives have helped shape …
Nuclear Factor Erythroid 2 Related Factor 2 and Mitochondria Form a Mutually Regulating Circuit in the Prevention and Treatment of Metabolic Syndrome
J Zhang, W Lv, G Zhang, M Zeng, W Cao… - Antioxidants & Redox …, 2024 - liebertpub.com
Significance: Metabolic syndrome (MetS) has become a major global public health problem
and there is an urgent need to elucidate its pathogenesis and find more effective targets and …
and there is an urgent need to elucidate its pathogenesis and find more effective targets and …
Examination of carnitine palmitoyltransferase 1 abundance in white adipose tissue: implications in obesity research
JD Warfel, B Vandanmagsar… - American Journal …, 2017 - journals.physiology.org
Carnitine palmitoyltransferase 1 (CPT1) is essential for the transport of long-chain fatty acids
into the mitochondria for oxidation. Recently, it was reported that decreased CPT1b mRNA …
into the mitochondria for oxidation. Recently, it was reported that decreased CPT1b mRNA …
The influence of serum selenium in differential epigenetic and transcriptional regulation of CPT1B gene in women with obesity
LM Watanabe, VAB Pereira, NY Noronha… - Journal of Trace …, 2024 - Elsevier
Introduction The increasing prevalence of obesity has become a major health problem
worldwide. The causes of obesity are multifactorial and could be influenced by dietary …
worldwide. The causes of obesity are multifactorial and could be influenced by dietary …
Metabolomic profiles of shift workers and day workers: a cross‐sectional study
X Huang, X Chen, S Zhao, J Hou, L Huang, J Xu… - …, 2021 - Wiley Online Library
Objective The purpose of this study was to characterize the metabolomic profiles of shift
workers and day workers and to discover the effect of shift work on workers' metabolic …
workers and day workers and to discover the effect of shift work on workers' metabolic …
Differential effects of fasting vs food restriction on liver thyroid hormone metabolism in male rats
EM de Vries, HC Van Beeren… - Journal of …, 2015 - joe.bioscientifica.com
Corticosteroid control of distal nephron sodium handling, particularly through the amiloride-
sensitive sodium channel (ENaC), has a key role in blood pressure regulation. The …
sensitive sodium channel (ENaC), has a key role in blood pressure regulation. The …