Osteoarthritis is a degenerative joint disease characterized by pain and disability. It involves
all ages and 70% of people aged> 65 have some degree of osteoarthritis. Natural cartilage …

With advanced properties similar to the native extracellular matrix, hydrogels have found
widespread applications in tissue engineering. Hydrogel-based cellular constructs have …

Improved biological and mechanical functionality of musculoskeletal tissue-engineered
constructs is required for clinical application, which can only be achieved by comprehensive …

Current developments in tissue engineering and microtechnology fields have allowed the
proposal of pertinent tools, microchips, to investigate in vitro toxicity. In the framework of the …

Bioreactors are important inevitable part of any tissue engineering (TE) strategy as they aid
the construction of three‐dimensional functional tissues. Since the ultimate aim of a …

Objective Hyaline cartilage degenerative pathologies induce morphologic and
biomechanical changes resulting in cartilage tissue damage. In pursuit of therapeutic …

Cell and tissue engineering are now being translated into clinical organ replacement,
offering alternatives to fight morbidity, organ shortages and ethico-social problems …

Articular cartilage experiences significant mechanical loads during daily activities. Healthy
cartilage provides the capacity for load bearing and regulates the mechanobiological …

We present a combined macro-scale/micro-scale computational approach to quantify
oxygen transport and flow-mediated shear stress to human chondrocytes cultured in three …

Tissue engineering is a multidisciplinary field that combines engineering, physical sciences,
biology, and medicine to restore or replace tissues and organs functions. In this review …