Kaempferol: A key emphasis to its anticancer potential

M Imran, B Salehi, J Sharifi-Rad, T Aslam Gondal… - Molecules, 2019 - mdpi.com
A marked decrease in human cancers, including breast cancer, bone cancer, and cervical
cancer, has been linked to the consumption of vegetable and fruit, and the corresponding …

Natural polyphenols for prevention and treatment of cancer

Y Zhou, J Zheng, Y Li, DP Xu, S Li, YM Chen, HB Li - Nutrients, 2016 - mdpi.com
There is much epidemiological evidence that a diet rich in fruits and vegetables could lower
the risk of certain cancers. The effect has been attributed, in part, to natural polyphenols …

Chemo‐preventive and therapeutic effect of the dietary flavonoid kaempferol: A comprehensive review

M Imran, A Rauf, ZA Shah, F Saeed… - Phytotherapy …, 2019 - Wiley Online Library
Kaempferol, a natural flavonoid present in several plants, possesses a wide range of
therapeutic properties such as antioxidant, anticancer, and anti‐inflammatory. It has a …

The upstream pathway of mTOR-mediated autophagy in liver diseases

H Wang, Y Liu, D Wang, Y Xu, R Dong, Y Yang, Q Lv… - Cells, 2019 - mdpi.com
Autophagy, originally found in liver experiments, is a cellular process that degrades
damaged organelle or protein aggregation. This process frees cells from various stress …

Cancer chemoprevention: A strategic approach using phytochemicals

M Swetha, CK Keerthana, TP Rayginia… - Frontiers in …, 2022 - frontiersin.org
Cancer chemoprevention approaches are aimed at preventing, delaying, or suppressing
tumor incidence using synthetic or natural bioactive agents. Mechanistically …

[HTML][HTML] Broad targeting of angiogenesis for cancer prevention and therapy

Z Wang, C Dabrosin, X Yin, MM Fuster, A Arreola… - Seminars in cancer …, 2015 - Elsevier
Deregulation of angiogenesis–the growth of new blood vessels from an existing vasculature–
is a main driving force in many severe human diseases including cancer. As such, tumor …

Therapeutic potential of vital transcription factors in Alzheimer's and Parkinson's disease with particular emphasis on transcription factor EB mediated autophagy

SN Rai, N Tiwari, P Singh, D Mishra, AK Singh… - Frontiers in …, 2021 - frontiersin.org
Autophagy is an important cellular self-digestion and recycling pathway that helps in
maintaining cellular homeostasis. Dysregulation at various steps of the autophagic and …

Antioxidant role of kaempferol in prevention of hepatocellular carcinoma

N Sharma, S Biswas, N Al-Dayan, AS Alhegaili… - Antioxidants, 2021 - mdpi.com
Reactive oxygen species (ROS) are noxious to cells because their increased level interacts
with the body's defense mechanism. These species also cause mutations and uncontrolled …

Autophagy and its role in gastric cancer

Y Cao, Y Luo, J Zou, J Ouyang, Z Cai, X Zeng, H Ling… - Clinica Chimica …, 2019 - Elsevier
Autophagy, which is tightly regulated by a series of autophagy-related genes (ATGs), is a
vital intracellular homeostatic process through which defective proteins and organelles are …

Kaempferol promotes non-small cell lung cancer cell autophagy via restricting Met pathway

R Wang, Z Deng, Z Zhu, J Wang, X Yang, M Xu… - Phytomedicine, 2023 - Elsevier
Background Kaempferol is extracted from Hedyotis diffusa, exerting an obvious anti-cancer
effect. Here in the present study, we explored the anti-cancer effects and mechanism of …