ATP is required for mammalian cells to remain viable and to perform genetically
programmed functions. Maintenance of the ΔG′ ATP hydrolysis of− 56 kJ/mole is the …

Ketogenic diets (KDs) have gained popularity among patients and researchers alike due to
their putative anti-tumor mechanisms. However, the question remains which conclusions …

Background Ketogenic metabolic therapy (KMT) using ketogenic diets (KD) is emerging as
viable alternative or complementary strategy for managing cancer; however, few clinical …

Very‐low‐carbohydrate diet triggers the endogenous production of ketone bodies as
alternative energy substrates. There are as yet unproven assumptions that ketone bodies …

Cancer cells (CCs) predominantly use aerobic glycolysis (Warburg effect) for their
metabolism. This important characteristic of CCs represents a potential metabolic pathway to …

Glioblastoma multiforme (GBM) is the most common and malignant of the primary adult brain
cancers. Ultrastructural and biochemical evidence shows that GBM cells exhibit …

Glioblastoma (GBM) is an aggressive primary human brain tumour that has resisted effective
therapy for decades. Although glucose and glutamine are the major fuels that drive GBM …

Ketogenic diets against cancer are worth further exploration, both in the laboratory and
clinically. Patients wishing to undertake a ketogenic diet during therapy should receive …

Background Aberrant metabolism is recognized as a hallmark of cancer, a pillar necessary
for cellular proliferation. Regarding bioenergetics (ATP generation), most cancers display a …

Background A growing body of evidence indicates the importance of nutrition in cancer
treatment. Ketogenic diets are one strategy that has been proposed to enhance traditional …