Eukaryotic cells use cytoskeletal motor proteins to transport many different intracellular
cargos. Numerous kinesins and myosins have evolved to cope with the various transport …

Secretory proteins are transported to the Golgi complex in vesicles that bud from the
endoplasmic reticulum. The cytoplasmic coat protein complex II (COPII) is responsible for …

Cellular versatility depends on accurate trafficking of diverse proteins to their organellar
destinations. For the secretory pathway (followed by approximately 30% of all proteins), the …

Protein traffic moving from the endoplasmic reticulum (ER) to the Golgi complex in
mammalian cells passes through the tubulovesicular membrane clusters of the ER-Golgi …

Regulation of the opposing kinesin and dynein motors that drive axonal transport is
essential to maintain neuronal homeostasis. Here, we examine coordination of motor activity …

The endoplasmic reticulum (ER) is an organelle that is responsible for many essential
subcellular processes. Interconnected narrow tubules at the periphery and thicker sheet-like …

The cortical endoplasmic reticulum (ER) network in plants is a highly dynamic structure, and
it contacts the plasma membrane (PM) at ER-PM anchor/contact sites. These sites are …

Molecular motors drive the transport of vesicles and organelles within the cell. Traditionally,
these transport processes have been considered separately from membrane trafficking …

Transport carriers regulate membrane flow between compartments of the secretory and
endocytic pathways in eukaryotic cells. Carrier biogenesis is assisted by microtubules, actin …

Gap Junction (GJ) channels, including the most common Connexin 43 (Cx43), have
fundamental roles in excitable tissues by facilitating rapid transmission of action potentials …